SCHEMBL30089730

SCHEMBL30089730

Oc1c(F)ccc2c1Cc1ccccc1-2

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.47
NPC1 O15118 3/20 0.45
RAB9A P51151 3/20 0.45
KDM4E B2RXH2 2/20 0.45
ALDH1A1 P00352 2/20 0.45
MAPT P10636 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
PGR P06401 1/20 0.40
HSP90AA1 P07900 1/20 0.40
LMNA P02545 1/20 0.39
HPGD P15428 1/20 0.39
HTR2B P41595 3/20 0.39
HTR7 P34969 2/20 0.39
SRD5A2 P31213 1/20 0.39
CYP1A2 P05177 3/20 0.37
CYP3A4 P08684 1/20 0.37
MAOA P21397 2/20 0.36
HTR2C P28335 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29927125 0.81 PNMT (0.50) PNMTNPC1RAB9AKDM4EALDH1A1
SCHEMBL1261848 0.81 PNMT (0.50) PNMTNPC1RAB9AKDM4EALDH1A1
SCHEMBL9811068 0.81 PNMT (0.46) PNMTNPC1RAB9AKDM4EALDH1A1
SCHEMBL3763958 0.78 PNMT (0.51) PNMTNPC1RAB9AKDM4EALDH1A1
SCHEMBL18242518 0.78 PNMT (0.43) PNMTNPC1RAB9AKDM4EALDH1A1
SCHEMBL15661976 0.78 PNMT (0.47) PNMTNPC1RAB9AKDM4EALDH1A1
SCHEMBL672642 0.78 PNMT (0.47) PNMTNPC1RAB9AKDM4EALDH1A1
SCHEMBL30102575 0.78 ALDH1A1 (0.49) PNMTNPC1RAB9AKDM4EALDH1A1
SCHEMBL29355284 0.78 PNMT (0.47) PNMTNPC1RAB9AKDM4EALDH1A1
SCHEMBL22263591 0.77 PNMT (0.57) PNMTNPC1RAB9AKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115551355-A Active compound combinations and fungicide compositions comprising them 拜耳公司 2022-12-30 CN disclosed