SCHEMBL9811068

SCHEMBL9811068

Fc1ccc2c(c1F)Cc1ccccc1-2

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.46
NPC1 O15118 3/20 0.41
RAB9A P51151 3/20 0.41
KDM4E B2RXH2 2/20 0.41
ALDH1A1 P00352 2/20 0.41
MAPT P10636 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
LMNA P02545 1/20 0.41
HPGD P15428 1/20 0.41
MAOA P21397 1/20 0.39
PGR P06401 1/20 0.39
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA4 P22748 1/20 0.38
CA6 P23280 1/20 0.38
HTR7 P34969 2/20 0.37
HTR2B P41595 2/20 0.37
SRD5A2 P31213 1/20 0.37
BCHE P06276 1/20 0.36
CES1 P23141 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18242518 0.81 PNMT (0.43) PNMTNPC1RAB9AKDM4EALDH1A1
SCHEMBL30089730 0.81 PNMT (0.47) PNMTNPC1RAB9AKDM4EALDH1A1
SCHEMBL24262482 0.80 SETD7 (0.34) PNMTNPC1RAB9AKDM4EALDH1A1
SCHEMBL22263591 0.80 PNMT (0.57) PNMTNPC1RAB9AKDM4EALDH1A1
SCHEMBL29090328 0.79 PNMT (0.46) PNMTNPC1RAB9AKDM4EALDH1A1
SCHEMBL4359047 0.79 PNMT (0.53) PNMTNPC1RAB9AKDM4EALDH1A1
SCHEMBL6555945 0.78 PNMT (0.41) PNMTNPC1RAB9AKDM4EALDH1A1
SCHEMBL28568070 0.78 PNMT (0.52) PNMTNPC1RAB9AKDM4EALDH1A1
SCHEMBL9125626 0.76 PGR (0.42) PNMTNPC1RAB9AKDM4EALDH1A1
SCHEMBL524602 0.75 PNMT (0.63) PNMTNPC1RAB9AKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250120252-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2025-04-10 US claimed
US-12178064-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2024-12-24 US claimed
US-12069939-B2 Method for patterning a coating on a surface and device including a patterned coating OTI LUMIONICS INC. (CA) 2024-08-20 US claimed
US-20230363196-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2023-11-09 US claimed
CN-116583131-A Method for patterning a surface coating and apparatus comprising a patterned coating OTI照明公司 2023-08-11 CN claimed
US-20230165124-A1 METHOD FOR PATTERNING A COATING ON A SURFACE AND DEVICE INCLUDING A PATTERNED COATING OTI LUMIONICS INC. (CA) 2023-05-25 US claimed
US-11581487-B2 Patterned conductive coating for surface of an opto-electronic device OTI LUMIONICS INC. (CA) 2023-02-14 US claimed
US-12590244-B2 Method for patterning a coating on a surface and device including a patterned coating OTI LUMIONICS INC. (CA) 2026-03-31 US disclosed
US-20250120252-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2025-04-10 US disclosed
US-20250024700-A1 DEVICE INCLUDING A CONDUCTIVE COATING DISPOSED OVER EMISSIVE REGIONS AND METHOD THEREFOR OTI Lumonics Inc. (CA) 2025-01-16 US disclosed
US-12178064-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2024-12-24 US disclosed
US-12150374-B2 Method for patterning a coating on a surface and device including a patterned coating OTI LUMIONICS INC. (CA) 2024-11-19 US disclosed
US-20240381754-A1 METHOD FOR PATTERNING A COATING ON A SURFACE AND DEVICE INCLUDING A PATTERNED COATING OTI LUMIONICS INC. (CA) 2024-11-14 US disclosed
US-4540700-A Treatment of diabetic complications with certain spiro-imidazolidine-diones ALCON LABORATORIES, INC. (US) 1985-09-10 US disclosed
US-4438272-A COMPLICATIONS OF DIABETES ALCON LABORATORIES, INC. (US) 1984-03-20 US disclosed
US-4436745-A TETRACYCLIC SPIROHYDANTOINS ALCON LABORATORIES, INC. (US) 1984-03-13 US disclosed
WO-1983003543-A1 METHOD OF INHIBITING ALDOSE REDUCTASE ACTIVITY, COMPOSITIONS THEREFOR AND PROCESS FOR PREPARING SPIRO-FLUOROFLUOREN AND SPIRO-DIFLUOROFLUOREN COMPOUNDS ALCON LAB INC (US) 1983-10-27 WO disclosed
WO-1983003543-A1 METHOD OF INHIBITING ALDOSE REDUCTASE ACTIVITY, COMPOSITIONS THEREFOR AND PROCESS FOR PREPARING SPIRO-FLUOROFLUOREN AND SPIRO-DIFLUOROFLUOREN COMPOUNDS ALCON LAB INC (US) 1983-10-27 WO disclosed
EP-0092385-A2 Hydantoin derivatives for use in inhibiting aldose reductase activity, compositions therefor and process for preparing spiro-fluoren compounds ALCON LABORATORIES, INC. (US) 1983-10-26 EP disclosed
EP-0092385-A2 Hydantoin derivatives for use in inhibiting aldose reductase activity, compositions therefor and process for preparing spiro-fluoren compounds ALCON LABORATORIES, INC. (US) 1983-10-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12590244-B2 Method for patterning a coating on a surface and device including a patterned coating FLNB, FZD7, ITGB6 PNMT 2442/4885NPC1 714/4885RAB9A 1827/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.