Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 11/20 | 0.45 |
| ▸ | VNN1 | O95497 | 1/20 | 0.38 |
| ▸ | TOP2A | P11388 | 3/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23927471 | 0.84 | GPR52 (0.39) | GPR52 | |
| SCHEMBL30091622 | 0.84 | GPR52 (0.39) | GPR52 | |
| SCHEMBL30091689 | 0.82 | RPS6KB1 (0.38) | GPR52PARP1 | |
| SCHEMBL30091570 | 0.81 | GPR52 (0.43) | GPR52 | |
| SCHEMBL30091639 | 0.77 | GPR52 (0.36) | GPR52PARP1 | |
| SCHEMBL15964837 | 0.77 | HCAR2 (0.46) | GPR52PARP1 | |
| SCHEMBL15964865 | 0.76 | MAOB (0.39) | — | |
| SCHEMBL30091470 | 0.75 | IDO1 (0.43) | GPR52JAK2JAK3PARP1 | |
| SCHEMBL30091540 | 0.75 | NR3C2 (0.48) | GPR52VNN1 | |
| SCHEMBL30091585 | 0.72 | KDM5A (0.41) | GPR52VNN1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166116-B | Amido bridged heterocyclic compound, and composition and application thereof | 北京赛特明强医药科技有限公司 | 2022-12-27 | — | — | CN | disclosed |