Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 5/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | APLNR | P35414 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23927471 | 1.00 | GPR52 (0.39) | GPR52ALOX5KDM4EMEN1HSP90AA1 | |
| SCHEMBL23927445 | 0.88 | NTRK1 (0.43) | ALOX5KDM4EMEN1MAPTKMT2A | |
| SCHEMBL23927479 | 0.85 | TSHR (0.39) | ALOX5KDM4EMEN1MAPTKMT2A | |
| SCHEMBL30091457 | 0.85 | TSHR (0.39) | ALOX5KDM4EMEN1MAPTKMT2A | |
| SCHEMBL30091645 | 0.84 | GPR52 (0.45) | GPR52 | |
| SCHEMBL23927435 | 0.82 | PDE3B (0.39) | GPR52ALOX5KDM4EMEN1MAPT | |
| SCHEMBL30091704 | 0.82 | PDE3B (0.39) | GPR52ALOX5KDM4EMEN1MAPT | |
| SCHEMBL18420957 | 0.81 | ALDH1A1 (0.39) | ALOX5KDM4EMEN1MAPTKMT2A | |
| SCHEMBL19207821 | 0.80 | PGR (0.39) | GPR52KDM4EMEN1MAPTKMT2A | |
| SCHEMBL29415696 | 0.80 | PGR (0.39) | GPR52KDM4EMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166116-B | Amido bridged heterocyclic compound, and composition and application thereof | 北京赛特明强医药科技有限公司 | 2022-12-27 | — | — | CN | disclosed |