Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 6/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GCGR | P47871 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23927454 | 1.00 | ALOX15 (0.45) | ALOX15ADORA3ALPLPDE3BPDE3A | |
| SCHEMBL23927464 | 0.89 | TSHR (0.46) | ALOX15NPC1RAB9AMAPK1ALDH1A1 | |
| SCHEMBL30091676 | 0.88 | KMT2A (0.38) | ALOX15PDE3BPDE3AMAPTNPC1 | |
| SCHEMBL23927442 | 0.88 | KMT2A (0.38) | ALOX15PDE3BPDE3AMAPTNPC1 | |
| SCHEMBL23927496 | 0.84 | KDM4E (0.40) | MAPTALDH1A1HPGDPOLBHSD17B10 | |
| SCHEMBL23927502 | 0.84 | MMP2 (0.41) | MAPTNPC1RAB9ALMNAMAPK1 | |
| SCHEMBL30091516 | 0.84 | P2RX7 (0.37) | ALOX15ALPLPDE3BPDE3AMAPT | |
| SCHEMBL23927439 | 0.84 | P2RX7 (0.37) | ALOX15ALPLPDE3BPDE3AMAPT | |
| SCHEMBL23927475 | 0.83 | PDE3B (0.42) | PDE3BPDE3AMAPTNPC1RAB9A | |
| SCHEMBL23927507 | 0.83 | HPGD (0.40) | ALOX15NPC1RAB9ALMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166116-B | Amido bridged heterocyclic compound, and composition and application thereof | 北京赛特明强医药科技有限公司 | 2022-12-27 | — | — | CN | disclosed |