Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30200215 | 0.98 | ALDH1A1 (0.50) | ALDH1A1TSHRHDAC8CA1CA2 | |
| Hydrochloric Acid SCHEMBL8990690 | 0.81 | KDM4E (0.32) | ALDH1A1TDP1 | |
| SCHEMBL30200152 | 0.77 | ALDH1A1 (0.46) | ALDH1A1TSHRHDAC8CA1CA2 | |
| Hydrochloric Acid SCHEMBL115619 | 0.74 | ALDH1A1 (0.52) | ALDH1A1TSHRHDAC8CA1CA2 | |
| Butane SCHEMBL28268770 | 0.73 | ALDH1A1 (0.69) | ALDH1A1TSHRHDAC8CA1CA2 | |
| SCHEMBL8720270 | 0.72 | — | — | |
| SCHEMBL15915 | 0.72 | ALDH1A1 (0.58) | ALDH1A1TSHRHDAC8CA1CA2 | |
| SCHEMBL13109192 | 0.71 | ALDH1A1 (0.50) | ALDH1A1TSHRHDAC8CA1CA2 | |
| SCHEMBL1119853 | 0.71 | ALDH1A1 (0.50) | ALDH1A1TSHRHDAC8CA1CA2 | |
| Hydrochloric Acid SCHEMBL419353 | 0.71 | CHRNA7 (0.50) | ALDH1A1TSHRHDAC8CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113088856-B | Deep eutectic solvent hot galvanizing additive and preparation method and application thereof | 江西科技师范大学 | 2022-12-23 | — | — | CN | disclosed |