SCHEMBL30097472

SCHEMBL30097472

OC[C@H]1O[C@@H](n2cnc3c(O)ncnc32)N[C@@H]1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ADORA3 P0DMS8 4/20 0.46
▸ ADORA2A P29274 4/20 0.46
▸ SMN1; SMN2 Q16637 3/20 0.46
▸ SLC29A1 Q99808 3/20 0.46
▸ MEN1 O00255 2/20 0.46
▸ ADORA2B P29275 2/20 0.46
▸ ADORA1 P30542 2/20 0.46
▸ KMT2A Q03164 2/20 0.46
▸ DPP4 P27487 1/20 0.46
▸ SLC28A1 O00337 1/20 0.46
▸ MAP3K7 O43318 1/20 0.46
▸ SLC28A2 O43868 1/20 0.46
▸ GAPDH P04406 1/20 0.46
▸ MAPK1 P28482 1/20 0.46
▸ STAT6 P42226 1/20 0.46
▸ PI4KA P42356 1/20 0.46
▸ PI4K2B Q8TCG2 1/20 0.46
▸ DOT1L Q8TEK3 1/20 0.46
▸ PI4K2A Q9BTU6 1/20 0.46
▸ SLC28A3 Q9HAS3 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL343881 1.00 ADORA3 (0.46) ADORA3ADORA2ASMN1; SMN2SLC29A1MEN1
SCHEMBL343882 1.00 ADORA3 (0.46) ADORA3ADORA2ASMN1; SMN2SLC29A1MEN1
SCHEMBL20268268 1.00 ADORA3 (0.46) ADORA3ADORA2ASMN1; SMN2SLC29A1MEN1
Inosine SCHEMBL298755 0.77 SLC29A1 (0.75) ADORA3ADORA2ASMN1; SMN2SLC29A1MEN1
Inosine SCHEMBL15804 0.77 SLC29A1 (0.75) ADORA3ADORA2ASMN1; SMN2SLC29A1MEN1
Inosine SCHEMBL4110068 0.77 SLC29A1 (0.75) ADORA3ADORA2ASMN1; SMN2SLC29A1MEN1
Inosine SCHEMBL6748954 0.77 SLC29A1 (0.75) ADORA3ADORA2ASMN1; SMN2SLC29A1MEN1
Inosine SCHEMBL12763613 0.77 SLC29A1 (0.75) ADORA3ADORA2ASMN1; SMN2SLC29A1MEN1
Inosine SCHEMBL20138477 0.77 SLC29A1 (0.75) ADORA3ADORA2ASMN1; SMN2SLC29A1MEN1
Inosine SCHEMBL2229394 0.77 SLC29A1 (0.75) ADORA3ADORA2ASMN1; SMN2SLC29A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025085691-A1 TRANS-SPLICING NUCLEIC ACID MOLECULES AND METHODS OF USE TACIT THERAPEUTICS, INC. (US) 2025-04-24 — — WO disclosed
EP-4508211-A2 THERAPEUTIC APPLICATIONS OF CRISPR TYPE V SYSTEMS Caribou Biosciences, Inc. (US) 2025-02-19 — — EP disclosed
CN-118974253-A Therapeutic application of CRISPR V-type system 卡里布生物科学公司 2024-11-15 — — CN disclosed
CN-118202051-A RNA editing by recruiting spliceosome components 泰思特治疗公司 2024-06-14 — — CN disclosed
EP-4359539-A1 OPTIMIZED ANTI-FLT1 OLIGONUCLEOTIDE COMPOUNDS FOR TREATMENT OF PREECLAMPSIA AND OTHER ANGIOGENIC DISORDERS University Of Massachusetts (US) 2024-05-01 — — EP disclosed
WO-2023201270-A2 THERAPEUTIC APPLICATIONS OF CRISPR TYPE V SYSTEMS CARIBOU BIOSCIENCES, INC. (US) 2023-10-19 — — WO disclosed
WO-2022271786-A1 OPTIMIZED ANTI-FLT1 OLIGONUCLEOTIDE COMPOUNDS FOR TREATMENT OF PREECLAMPSIA AND OTHER ANGIOGENIC DISORDERS UNIVERSITY OF MASSACHUSETTS (US) 2022-12-29 — — WO disclosed
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