Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TGM2 | P21980 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL988048 | 0.90 | THRB (0.57) | THRBALDH1A1TSHRCYP3A4MAPT | |
| SCHEMBL7633786 | 0.85 | THRB (0.51) | THRBALDH1A1TSHRCYP3A4MAPT | |
| SCHEMBL28440322 | 0.80 | THRB (0.51) | THRBALDH1A1TSHRCYP3A4MAPT | |
| SCHEMBL28356625 | 0.79 | LMNA (0.57) | ALDH1A1MAPTNPC1RECQLRAB9A | |
| SCHEMBL10627202 | 0.78 | THRB (0.43) | THRBALDH1A1CYP3A4MAPTTGM2 | |
| SCHEMBL11054572 | 0.78 | HDAC8 (0.55) | THRBALDH1A1TSHRCYP3A4HDAC3 | |
| SCHEMBL29085550 | 0.78 | DRD2 (0.55) | THRBNPC1RECQLRAB9ASMN1; SMN2 | |
| SCHEMBL8349531 | 0.78 | TDP1 (0.68) | ALDH1A1CYP3A4MAPTHPGDHIF1A | |
| SCHEMBL16039243 | 0.77 | HCAR2 (0.51) | THRBALDH1A1MAPTLMNATDP1 | |
| SCHEMBL20615035 | 0.77 | SMN1; SMN2 (0.54) | THRBALDH1A1TSHRCYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2657304-B1 | AZO DYE, OCULAR LENS MATERIAL, METHOD FOR PRODUCING OCULAR LENS MATERIAL, AND OCULAR LENS | MENICON CO LTD (JP) | 2022-12-07 | — | — | EP | disclosed |