Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 13/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 12/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 11/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 11/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 10/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 10/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 9/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 8/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 8/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 8/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 8/20 | 0.55 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25775259 | 1.00 | HDAC1 (0.55) | HDAC1HDAC6HDAC3HDAC2HDAC11 | |
| SCHEMBL30914249 | 0.88 | ALDH1A1 (0.55) | NOTUMKDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL29227032 | 0.88 | ALDH1A1 (0.55) | NOTUMKDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL30702196 | 0.85 | ALDH1A1 (0.57) | NOTUMKDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL1783365 | 0.83 | SMN1; SMN2 (0.57) | NOTUMKDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL28218368 | 0.82 | MAPT (0.58) | NOTUMKDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL29639131 | 0.78 | RAB9A (0.57) | NOTUMKDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL27022341 | 0.78 | RAB9A (0.57) | NOTUMKDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL28167267 | 0.78 | MAPT (0.61) | NOTUMKDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL30702167 | 0.78 | KDM4E (0.51) | NOTUMKDM4EALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240254107-A1 | RNA-TARGETING LIGANDS, COMPOSITIONS THEREOF, AND METHODS OF MAKING AND USING THE SAME | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2024-08-01 | — | — | US | disclosed |
| EP-4337653-A1 | RNA-TARGETING LIGANDS, COMPOSITIONS THEREOF, AND METHODS OF MAKING AND USING THE SAME | The University of North Carolina at Chapel Hill (US) | 2024-03-20 | — | — | EP | disclosed |
| WO-2022256382-A1 | RNA-TARGETING LIGANDS, COMPOSITIONS THEREOF, AND METHODS OF MAKING AND USING THE SAME | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2022-12-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240254107-A1 | RNA-TARGETING LIGANDS, COMPOSITIONS THEREOF, AND METHODS OF MAKING AND USING THE SAME | TARBP1, RNGTT, NSUN3 | HDAC1 3990/4885HDAC6 1839/4885HDAC3 1701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.