Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 2/20 | 0.47 |
| ▸ | FEN1 | P39748 | 2/20 | 0.47 |
| ▸ | HNF4A | P41235 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 2/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
| ▸ | ALB | P02768 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28025506 | 0.88 | ALOX5AP (0.47) | ALOX5APFEN1IDO1BCAT2KEAP1 | |
| SCHEMBL3234092 | 0.85 | ALOX5AP (0.60) | ALOX5APFEN1IDO1BCAT2ACMSD | |
| SCHEMBL28025518 | 0.83 | IDO1 (0.46) | ALOX5APFEN1IDO1BCAT2ERN1 | |
| SCHEMBL18317987 | 0.83 | HNF4A (0.56) | HNF4ABCAT2KEAP1NFE2L2HSD17B14 | |
| SCHEMBL18317872 | 0.83 | HNF4A (0.60) | HNF4ABCAT2KEAP1NFE2L2CHEK1 | |
| SCHEMBL2530485 | 0.81 | HSD17B1 (0.49) | NFE2L2ACMSDHSD17B1HSD17B2 | |
| SCHEMBL1892489 | 0.78 | HNF4A (0.55) | HNF4ABCAT2KEAP1NFE2L2CHEK1 | |
| SCHEMBL3453931 | 0.77 | HNF4A (0.53) | HNF4ABCAT2KEAP1NFE2L2PARP1 | |
| SCHEMBL8888647 | 0.76 | HNF4A (0.72) | HNF4ABCAT2KEAP1NFE2L2PARP1 | |
| SCHEMBL29838619 | 0.76 | HNF4A (0.72) | HNF4ABCAT2KEAP1NFE2L2PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4093401-A1 | SALICYLAMIDE DERIVATIVES AND RELATED METHODS OF MAKING | The Board of Regents of the University of Texas System (US) | 2022-11-30 | — | — | EP | disclosed |