Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 1/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 2/20 | 0.40 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 2/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28025506 | 0.90 | ALOX5AP (0.47) | IDO1DHODHKEAP1NFE2L2ALOX5AP | |
| SCHEMBL27730964 | 0.86 | HSD17B1 (0.49) | KEAP1NFE2L2ALOX5APFEN1KDM4E | |
| SCHEMBL27710591 | 0.86 | HSD17B1 (0.49) | KEAP1NFE2L2DGAT1CASP1KDM4E | |
| SCHEMBL27731122 | 0.85 | CASP1 (0.57) | AURKARPS6KB1CASP1ALDH1A1PARP1 | |
| SCHEMBL27731056 | 0.85 | ALOX5AP (0.39) | DHODHKEAP1NFE2L2ALOX5APFEN1 | |
| SCHEMBL27731009 | 0.85 | KIF11 (0.51) | KEAP1NFE2L2ALOX5APFEN1DGAT1 | |
| SCHEMBL27710593 | 0.85 | ALDH1A1 (0.40) | KEAP1NFE2L2ALOX5APFEN1DGAT1 | |
| SCHEMBL27730963 | 0.85 | DGAT1 (0.45) | KEAP1NFE2L2ALOX5APFEN1DGAT1 | |
| SCHEMBL27731047 | 0.85 | MAP2 (0.44) | KEAP1NFE2L2ALOX5APFEN1DGAT1 | |
| SCHEMBL30100407 | 0.83 | ALOX5AP (0.47) | IDO1DHODHKEAP1NFE2L2ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103739513-B | 4-methoxyl group-1,3-phenyl-diformyl aminated compounds and application thereof | TIANJIN UNIVERSITY OF TECHNOLOGY (CN) | 2015-09-23 | — | — | CN | disclosed |