Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.59 |
| ▸ | GNAI3 | P08754 | 3/20 | 0.55 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.55 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.55 |
| ▸ | PRCP | P42785 | 2/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27339475 | 0.97 | NAAA (0.55) | NAAAGNAI3GNAO1GNAI1PRCP | |
| SCHEMBL27339488 | 0.97 | NAAA (0.55) | NAAAGNAI3GNAO1GNAI1PRCP | |
| SCHEMBL27339534 | 0.97 | NAAA (0.55) | NAAAGNAI3GNAO1GNAI1PRCP | |
| SCHEMBL1237385 | 0.90 | NAAA (0.71) | NAAAGNAI3GNAO1GNAI1PRCP | |
| SCHEMBL8604694 | 0.90 | NAAA (0.71) | NAAAGNAI3GNAO1GNAI1PRCP | |
| SCHEMBL8604692 | 0.90 | NAAA (0.71) | NAAAGNAI3GNAO1GNAI1PRCP | |
| SCHEMBL1237387 | 0.90 | NAAA (0.71) | NAAAGNAI3GNAO1GNAI1PRCP | |
| SCHEMBL1238078 | 0.90 | NAAA (0.71) | NAAAGNAI3GNAO1GNAI1PRCP | |
| SCHEMBL1238081 | 0.90 | NAAA (0.71) | NAAAGNAI3GNAO1GNAI1PRCP | |
| SCHEMBL27339525 | 0.87 | NAAA (0.47) | NAAAGNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12605464-B2 | Cyclohexane lipidoids for nucleic acid transfection and use thereof | USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I. (CZ) | 2026-04-21 | — | — | US | disclosed |
| US-20240335559-A1 | CYCLOHEXANE LIPIDOIDS FOR NUCLEIC ACID TRANSFECTION AND USE THEREOF | USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I. (CZ) | 2024-10-10 | — | — | US | disclosed |
| EP-4373804-A1 | CYCLOHEXANE LIPIDOIDS FOR NUCLEIC ACID TRANSFECTION AND USE THEREOF | Ustav Organicke Chemie a Biochemie AV CR v.v.i. (CZ) | 2024-05-29 | — | — | EP | disclosed |
| WO-2023001323-A1 | CYCLOHEXANE LIPIDOIDS FOR NUCLEIC ACID TRANSFECTION AND USE THEREOF | Ustav Organicke Chemie A Biochemie AV CR v.v.i. (CZ) | 2023-01-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240335559-A1 | CYCLOHEXANE LIPIDOIDS FOR NUCLEIC ACID TRANSFECTION AND USE THEREOF | SGMS2, NR1H3, SGMS1 | NAAA 1973/4885GNAI3 2026/4885GNAO1 1147/4885 |
| US-12605464-B2 | Cyclohexane lipidoids for nucleic acid transfection and use thereof | NR1H2, NPC1, NR1H3 | NAAA 2391/4885GNAI3 2050/4885GNAO1 904/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.