SCHEMBL1237387

SCHEMBL1237387

CCCCCCCCCCCCNC(=O)C1C[C@H](C(=O)NCCCCCCCCCCCC)C[C@H](C(=O)NCCCCCCCCCCCC)C1

nearest known ligand 0.71

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.71
GNAI3 P08754 3/20 0.65
GNAO1 P09471 3/20 0.65
GNAI1 P63096 3/20 0.65
PRCP P42785 2/20 0.59
EPHX1 P07099 5/20 0.57
CASP2 P42575 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1238078 1.00 NAAA (0.71) NAAAGNAI3GNAO1GNAI1PRCP
SCHEMBL8604692 1.00 NAAA (0.71) NAAAGNAI3GNAO1GNAI1PRCP
SCHEMBL8604694 1.00 NAAA (0.71) NAAAGNAI3GNAO1GNAI1PRCP
SCHEMBL1237385 1.00 NAAA (0.71) NAAAGNAI3GNAO1GNAI1PRCP
SCHEMBL1238081 1.00 NAAA (0.71) NAAAGNAI3GNAO1GNAI1PRCP
SCHEMBL19141890 0.93 NAAA (0.63) NAAAGNAI3GNAO1GNAI1PRCP
SCHEMBL5416515 0.90 NAAA (0.59) NAAAGNAI3GNAO1GNAI1
SCHEMBL5416269 0.90 NAAA (0.59) NAAAGNAI3GNAO1GNAI1
SCHEMBL5418983 0.90 NAAA (0.59) NAAAGNAI3GNAO1GNAI1
SCHEMBL5413543 0.90 NAAA (0.59) NAAAGNAI3GNAO1GNAI1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7820146-B2 Care and/or make-up cosmetic composition structured with silicone polymers and organogelling agents, in rigid form L'OREAL S.A. (FR) 2010-10-26 US claimed
US-20050245673-A1 Care and/or make-up cosmetic composition structured with silicone polymers and organogelling agents, in rigid form L'OREAL S.A. (FR) 2005-11-03 US claimed
US-20040223987-A1 Composition structured with a polymer containing a heteroatom and organogelator L'OREAL S.A. (FR) 2004-11-11 US claimed
EP-1068854-B1 Solid form composition comprising an oil and a specific gelling agent, process for cosmetic treatment and use of this compound OREAL (FR) 2004-08-18 EP claimed
WO-2002047628-A1 COMPOSITION STRUCTURED WITH A POLYMER CONTAINING A HETEROATOM AND AN ORGANOGELATOR L'ORÉAL (FR) 2002-06-20 WO claimed
US-6372235-B1 Compositions in solid form comprising an oil and a specific gelling compound, cosmetic treatment processes, and use of the compound L'OREAL, S.A. (FR) 2002-04-16 US claimed
EP-1068854-A1 Solid form composition comprising an oil and a specific gelling agent, process for cosmetic treatment and use of this compound L'OREAL (FR) 2001-01-17 EP claimed
JP-10212213-A None JP disclosed
EP-1676556-B1 Cosmetic composition containing a polyorganosiloxane polymer OREAL (FR) 2012-01-11 EP disclosed
US-20110189117-A1 COSMETIC COMPOSITION CONTAINING A POLYORGANISILOXANE POLYMER L'OREAL (FR) 2011-08-04 US disclosed
US-7879316-B2 Mixture of polyamide-siloxane copolymer in volatile oil; cosmetics L'OREAL (FR) 2011-02-01 US disclosed
US-7820146-B2 Care and/or make-up cosmetic composition structured with silicone polymers and organogelling agents, in rigid form L'OREAL S.A. (FR) 2010-10-26 US disclosed
US-7803356-B2 Compositions containing at least one silicone resin and a volatile non-cyclic silicone oil L'OREAL (FR) 2010-09-28 US disclosed
US-20030091520-A1 Use of at least one polar additive in a cosmetic composition comprising a liquid fatty phase structured by at least one molecular organogelator, to impart a thixotropic character to the composition L'OREAL (FR) 2003-05-15 US disclosed
EP-1264589-A1 Use of a polar additive in a cosmetic composition containing a structured liquid oil phase by at least one organogelator to give a thixotropic character L'OREAL (FR) 2002-12-11 EP disclosed
WO-2002047628-A1 COMPOSITION STRUCTURED WITH A POLYMER CONTAINING A HETEROATOM AND AN ORGANOGELATOR L'ORÉAL (FR) 2002-06-20 WO disclosed
US-6372235-B1 Compositions in solid form comprising an oil and a specific gelling compound, cosmetic treatment processes, and use of the compound L'OREAL, S.A. (FR) 2002-04-16 US disclosed
JP-2001058915-A SOLID COMPOSITION COMPRISING OIL AND SPECIFIC GEL COMPOUND, BEAUTY TREATMENT AND USE OF THE SAME COMPOUND L'OREAL SA 2001-03-06 JP disclosed
EP-1068854-A1 Solid form composition comprising an oil and a specific gelling agent, process for cosmetic treatment and use of this compound L'OREAL (FR) 2001-01-17 EP disclosed
JP-H10212213-A COMPOSITION CONTAINING CYCLOHEXANETRICARBOXAMIDE DERIVATIVE POLA CHEM IND INC 1998-08-11 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040223987-A1 Composition structured with a polymer containing a heteroatom and organogelator CUTA, PARG, FABP4 NAAA 1903/4885GNAI3 3528/4885GNAO1 4473/4885
US-20110189117-A1 COSMETIC COMPOSITION CONTAINING A POLYORGANISILOXANE POLYMER CUTA, PRDX1, PRXL2A NAAA 4180/4885GNAI3 3591/4885GNAO1 2711/4885
US-20030091520-A1 Use of at least one polar additive in a cosmetic composition comprising a liquid fatty phase structured by at least one molecular organogelator, to impart a thixotropic character to the composition PLIN3, CUTA, FABP4 NAAA 1779/4885GNAI3 1907/4885GNAO1 3552/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.