Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 8/20 | 0.50 |
| ▸ | KDM5C | P41229 | 7/20 | 0.50 |
| ▸ | KDM4A | O75164 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | KDM5B | Q9UGL1 | 5/20 | 0.50 |
| ▸ | KDM6B | O15054 | 4/20 | 0.50 |
| ▸ | KDM2A | Q9Y2K7 | 4/20 | 0.50 |
| ▸ | KDM3A | Q9Y4C1 | 4/20 | 0.50 |
| ▸ | KDM5A | P29375 | 3/20 | 0.50 |
| ▸ | KDM4D | Q6B0I6 | 2/20 | 0.50 |
| ▸ | ALKBH5 | Q6P6C2 | 2/20 | 0.50 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.50 |
| ▸ | TET3 | O43151 | 1/20 | 0.50 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ASPH | Q12797 | 1/20 | 0.50 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.50 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.50 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23989390 | 1.00 | KDM4C (0.50) | KDM4CKDM5CKDM4AKDM4EKDM5B | |
| SCHEMBL30209656 | 0.85 | CYP1A2 (0.42) | KDM4CKDM5CKDM4EKDM5BKDM5A | |
| SCHEMBL28298258 | 0.85 | CYP1A2 (0.39) | KDM4CKDM5CKDM4AKDM4EKDM5B | |
| SCHEMBL27850448 | 0.85 | CYP1A2 (0.42) | KDM4CKDM5CKDM4EKDM5BKDM5A | |
| SCHEMBL23990564 | 0.81 | KDM4E (0.51) | KDM4CKDM5CKDM4EKDM5BKDM6B | |
| SCHEMBL30281068 | 0.80 | KDM4E (0.50) | KDM4CKDM5CKDM4EKDM5BKDM6B | |
| SCHEMBL5567317 | 0.80 | ALDH1A1 (0.55) | KDM4CKDM5CKDM4AKDM4EKDM5B | |
| SCHEMBL3912359 | 0.79 | KDM4C (0.49) | KDM4CKDM5CKDM4AKDM4EKDM5B | |
| SCHEMBL7670706 | 0.78 | KDM4C (0.57) | KDM4CKDM5CKDM4AKDM4EKDM5B | |
| SCHEMBL2305108 | 0.78 | KDM4C (0.57) | KDM4CKDM5CKDM4AKDM4EKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115867348-A | Imidazopyrimidines as IL-17 modulators | 詹森药业有限公司 | 2023-03-28 | — | — | CN | disclosed |
| EP-4143193-A1 | IMIDAZOPYRIMIDINES AS MODULATORS OF IL-17 | JANSSEN Pharmaceutica NV (BE) | 2023-03-08 | — | — | EP | disclosed |
| EP-4093400-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | The Trustees of Princeton University (US) | 2022-11-30 | — | — | EP | disclosed |