Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KDM5C | P41229 | 3/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.42 |
| ▸ | KDM5A | P29375 | 1/20 | 0.42 |
| ▸ | KDM5D | Q9BY66 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDM4B | O94953 | 1/20 | 0.41 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27850448 | 1.00 | CYP1A2 (0.42) | CYP1A2POLBKDM5CKDM5BKDM4C | |
| SCHEMBL23989390 | 0.85 | KDM4C (0.50) | KDM5CKDM5BKDM4CKDM5AKDM4E | |
| SCHEMBL30100697 | 0.85 | KDM4C (0.50) | KDM5CKDM5BKDM4CKDM5AKDM4E | |
| SCHEMBL28298258 | 0.83 | CYP1A2 (0.39) | CYP1A2POLBKDM5CKDM5BKDM4C | |
| SCHEMBL23990564 | 0.80 | KDM4E (0.51) | KDM5CKDM5BKDM4CKDM5AKDM4E | |
| SCHEMBL30607268 | 0.79 | CYP1A2 (0.47) | CYP1A2POLBKDM5CKDM5BKDM4C | |
| SCHEMBL8594535 | 0.79 | CYP1A2 (0.47) | CYP1A2POLBKDM5CKDM5BKDM4C | |
| SCHEMBL7668183 | 0.79 | CYP1A2 (0.47) | CYP1A2POLBKDM5CKDM5BKDM4C | |
| SCHEMBL509023 | 0.79 | CYP1A2 (0.47) | CYP1A2POLBKDM5CKDM5BKDM4C | |
| SCHEMBL30281068 | 0.78 | KDM4E (0.50) | KDM5CKDM5BKDM4CKDM5AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115867348-A | Imidazopyrimidines as IL-17 modulators | 詹森药业有限公司 | 2023-03-28 | — | — | CN | disclosed |
| EP-4143195-A1 | IMIDAZOPYRIDAZINES AS MODULATORS OF IL-17 | Janssen Pharmaceutica NV (BE) | 2023-03-08 | — | — | EP | disclosed |