Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3389475 | 1.00 | POLB (0.51) | POLBCYP2A6SRD5A1OPRM1OPRK1 | |
| SCHEMBL8164410 | 0.88 | MEN1 (0.50) | POLBCYP2A6MEN1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1977939 | 0.86 | MEN1 (0.49) | POLBCYP2A6MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11677341 | 0.84 | HTR2A (0.50) | POLBSRD5A1OPRM1OPRK1HTR2A | |
| Hydrochloric Acid SCHEMBL11818641 | 0.82 | HTR2A (0.48) | POLBSRD5A1OPRM1OPRK1HTR2A | |
| SCHEMBL1462133 | 0.81 | HPGD (0.55) | CYP2A6OPRM1OPRK1OPRL1MEN1 | |
| SCHEMBL30642087 | 0.81 | HPGD (0.55) | CYP2A6OPRM1OPRK1OPRL1MEN1 | |
| Hydrochloric Acid SCHEMBL27671303 | 0.79 | HPGD (0.53) | CYP2A6OPRM1OPRK1OPRL1MEN1 | |
| SCHEMBL26077071 | 0.79 | HRH1 (0.51) | POLBCYP2A6SRD5A1MEN1KMT2A | |
| SCHEMBL761220 | 0.75 | SRD5A1 (0.54) | POLBCYP2A6SRD5A1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4093400-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | The Trustees of Princeton University (US) | 2022-11-30 | — | — | EP | disclosed |