Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | CDK4 | P11802 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CCND1 | P24385 | 1/20 | 0.46 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SLC22A2 | O15244 | 2/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.41 |
| ▸ | SLC22A3 | O75751 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11818641 | 0.97 | HTR2A (0.48) | HTR2AMEN1KMT2AALDH1A1USP2 | |
| SCHEMBL3389475 | 0.84 | POLB (0.51) | HTR2AMEN1KMT2AHSD17B3NPC1 | |
| SCHEMBL30100746 | 0.84 | POLB (0.51) | HTR2AMEN1KMT2AHSD17B3NPC1 | |
| SCHEMBL12320654 | 0.84 | HPGD (0.42) | HTR2AMEN1KMT2AALDH1A1USP2 | |
| SCHEMBL21153126 | 0.77 | HSD17B3 (0.52) | HTR2AMEN1KMT2AALDH1A1USP2 | |
| SCHEMBL8164410 | 0.77 | MEN1 (0.50) | MEN1KMT2ASIGMAR1SMN1; SMN2LMNA | |
| SCHEMBL5047321 | 0.76 | — | — | |
| SCHEMBL29625280 | 0.75 | MEN1 (0.54) | HTR2AMEN1KMT2AALDH1A1USP2 | |
| SCHEMBL112247 | 0.75 | MEN1 (0.54) | HTR2AMEN1KMT2AALDH1A1USP2 | |
| Hydrochloric Acid SCHEMBL1977939 | 0.75 | MEN1 (0.49) | MEN1KMT2AALDH1A1SIGMAR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200321533-A1 | COMPOUNDS FOR ORGANIC LIGHT EMITTING DIODE MATERIALS | THE SCRIPPS RESEARCH INSTITUTE | 2020-10-08 | — | — | US | disclosed |
| WO-2019161781-A1 | RECEPTOR ANTAGONIST, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USAGE THEREOF | 北京泰德制药股份有限公司 | 2019-08-29 | — | — | WO | disclosed |
| US-20180212158-A1 | ORGANIC LIGHT-EMITTING DIODE MATERIALS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2018-07-26 | — | — | US | disclosed |
| US-20170244049-A1 | ORGANIC LIGHT-EMITTING DIODE MATERIALS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-08-24 | — | — | US | disclosed |
| WO-2017044567-A1 | HETEROCYCLIC CONSTRAINED TRICYCLIC SULFONAMIDES AS ANTI-CANCER AGENTS | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2017-03-16 | — | — | WO | disclosed |
| WO-2017011531-A2 | ORGANIC LIGHT-EMITTING DIODE MATERIALS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-01-19 | — | — | WO | disclosed |
| US-4018930-A | ANALGESICS, SEDATIVES, TRANQUILIZERS | ENDO LABORATORIES, INC. (US) | 1977-04-19 | — | — | US | disclosed |
| US-3983123-A | CNS ANTIDEPRESSANTS | ENDO LABORATORIES, INC. (US) | 1976-09-28 | — | — | US | disclosed |
| US-3966762-A | N-[6,7]-Dihydroindolo[1,7-ab][1]benzazepin-2-yl)methyl/phthalimide | STERLING DRUG INC. (US) | 1976-06-29 | — | — | US | disclosed |
| US-3963721-A | 2-(Piperazinoethyl)-6,7-dihydroindol)[1,7-an] [1]benzazepine | STERLING DRUG INC. (US) | 1976-06-15 | — | — | US | disclosed |
| US-3947447-A | CENTRAL NERVOUS SYSTEM DEPRESSANT, ANTICONVULSANT, MUSCLE RELAXANT, HYPOTENSIVE | AMERICAN HOECHST CORPORATION (US) | 1976-03-30 | — | — | US | disclosed |
| US-3932650-A | TRANQUILIZERS | E. I. DU PONT DE NEMOURS & COMPANY (US) | 1976-01-13 | — | — | US | disclosed |
| US-3931223-A | 3-(Dimethylamino)-1,2,3,4,8,9-hexahydro-1H[1]benzazepino[1,2,3-k,j]carbazole | STERLING DRUG INC. (US) | 1976-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200321533-A1 | COMPOUNDS FOR ORGANIC LIGHT EMITTING DIODE MATERIALS | ALDH1A2, DDT, CLTB | HTR2A 1011/4885MEN1 2493/4885KMT2A 2223/4885 |
| US-20180212158-A1 | ORGANIC LIGHT-EMITTING DIODE MATERIALS | MSN, DDT, NECTIN4 | HTR2A 861/4885MEN1 122/4885KMT2A 1200/4885 |
| US-20170244049-A1 | ORGANIC LIGHT-EMITTING DIODE MATERIALS | CYBA, DDT, DRD1 | HTR2A 1849/4885MEN1 2440/4885KMT2A 1916/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.