Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9852647 | 0.85 | MAOA (0.50) | CES1ALDH1A1KDM4ECYP3A4KMT2A | |
| SCHEMBL11677341 | 0.80 | HTR2A (0.50) | HRH1SLC6A4ALDH1A1KDM4ECYP3A4 | |
| SCHEMBL30100746 | 0.79 | POLB (0.51) | CES1KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL3389475 | 0.79 | POLB (0.51) | CES1KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL23569664 | 0.78 | HRH1 (0.51) | HRH1SLC6A4CES1ALDH1A1KDM4E | |
| SCHEMBL12059599 | 0.78 | NR1H2 (0.59) | HRH1SLC6A4CES1ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL11818641 | 0.78 | HTR2A (0.48) | HRH1SLC6A4ALDH1A1KDM4ECYP3A4 | |
| SCHEMBL12142340 | 0.74 | HRH1 (0.51) | HRH1SLC6A4CES1ALDH1A1KDM4E | |
| SCHEMBL12043655 | 0.74 | HRH1 (0.51) | HRH1SLC6A4CES1ALDH1A1KDM4E | |
| SCHEMBL31019547 | 0.73 | BCAT2 (0.50) | CES1ALDH1A1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023180484-A1 | ANTIBODY-CONJUGATES FOR TARGETING OF TUMOURS EXPRESSING PTK7 | SYNAFFIX B.V. (NL) | 2023-09-28 | — | — | WO | disclosed |
| WO-2023180490-A1 | ANTIBODY-CONJUGATES FOR TARGETING OF TUMOURS EXPRESSING NECTIN-4 | SYNAFFIX B.V. (NL) | 2023-09-28 | — | — | WO | disclosed |