Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 18/20 | 0.57 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26441299 | 1.00 | BRD4 (0.57) | BRD4ALKCRBN | |
| SCHEMBL14756076 | 0.85 | BRD4 (0.61) | BRD4 | |
| SCHEMBL31329495 | 0.83 | MAP4K1 (0.51) | CRBN | |
| SCHEMBL21646064 | 0.83 | MAP4K1 (0.51) | CRBN | |
| SCHEMBL31329494 | 0.83 | MAP4K1 (0.51) | CRBN | |
| SCHEMBL26089057 | 0.82 | KDR (0.37) | BRD4ALKCRBN | |
| SCHEMBL26086551 | 0.81 | BRD4 (0.39) | BRD4CRBN | |
| SCHEMBL26086646 | 0.81 | OTUD7B (0.38) | BRD4ALKCRBN | |
| SCHEMBL30100774 | 0.81 | BRD4 (0.39) | BRD4CRBN | |
| SCHEMBL16771576 | 0.80 | BRD4 (0.58) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230128402-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | THE TRUSTEES OF PRINCETON UNIVERSITY | 2023-04-27 | — | — | US | disclosed |
| EP-4093400-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | The Trustees of Princeton University (US) | 2022-11-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230128402-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | PAH, ALDH2, IDH2 | BRD4 684/4885ALK 701/4885CRBN 3317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.