SCHEMBL30100976

SCHEMBL30100976

Clc1csc(C2CNCCO2)c1

nearest known ligand 0.46

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.41
DRD3 P35462 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30100952 0.81 HTR1A (0.41) DRD2DRD3
SCHEMBL31412602 0.75 HTR3A (0.49)
SCHEMBL27892863 0.74 DRD2 (0.48) DRD2DRD3
SCHEMBL1636926 0.73 DRD2 (0.53) DRD2DRD3
SCHEMBL1690578 0.73 DRD2 (0.53) DRD2DRD3
SCHEMBL1690925 0.73 DRD2 (0.53) DRD2DRD3
Hydrochloric Acid SCHEMBL16970832 0.71 DRD2 (0.51) DRD2DRD3
SCHEMBL7010502 0.71 DRD2 (0.47) DRD2DRD3
SCHEMBL11681496 0.71 DRD2 (0.68) DRD2DRD3
Hydrochloric Acid SCHEMBL16462135 0.70 DRD2 (0.66) DRD2DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115433205-A Polycyclic derivative receptor agonist, preparation method and application thereof 上海翰森生物医药科技有限公司 2022-12-06 CN disclosed