Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 4/20 | 0.36 |
| ▸ | HTR2A | P28223 | 3/20 | 0.36 |
| ▸ | HTR2B | P41595 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | PNMT | P11086 | 1/20 | 0.34 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.32 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.32 |
| ▸ | HTR3B | O95264 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.32 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.31 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL868555 | 1.00 | CHRNB2 (0.38) | CHRNB2CHRNA4HTR2CHTR2AHTR2B | |
| Hydrochloric Acid SCHEMBL30345777 | 0.98 | CHRNB2 (0.37) | CHRNB2CHRNA4HTR2CHTR2AHTR2B | |
| Hydrochloric Acid SCHEMBL20723245 | 0.98 | CHRNB2 (0.37) | CHRNB2CHRNA4HTR2CHTR2AHTR2B | |
| Trifluoroacetic Acid SCHEMBL18550357 | 0.83 | ABHD6 (0.41) | CHRNB2CHRNA4ABHD6 | |
| SCHEMBL29361127 | 0.82 | PNMT (0.47) | HTR2CHTR2AHTR2BPNMTASIC3 | |
| SCHEMBL868598 | 0.82 | PNMT (0.47) | HTR2CHTR2AHTR2BPNMTASIC3 | |
| SCHEMBL12691385 | 0.82 | PNMT (0.47) | HTR2CHTR2AHTR2BPNMTASIC3 | |
| Hydrochloric Acid SCHEMBL12541304 | 0.80 | PNMT (0.47) | HTR2CHTR2AHTR2BPNMTASIC3 | |
| Hydrochloric Acid SCHEMBL1017773 | 0.80 | PNMT (0.46) | HTR2CHTR2BPNMTASIC3 | |
| Hydrochloric Acid SCHEMBL31226197 | 0.80 | PNMT (0.46) | HTR2CHTR2BPNMTASIC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4662208-A1 | COMPOUNDS AND COMPOSITIONS FOR SELECTIVE DEGRADATION OF ENGINEERED PROTEINS | Celgene Corporation (US) | 2025-12-17 | — | — | EP | disclosed |
| US-20250034120-A1 | PYRIDAZINONES AS PARP7 INHIBITORS | RIBON THERAPEUTICS, INC. | 2025-01-30 | — | — | US | disclosed |
| WO-2024167999-A1 | COMPOUNDS AND COMPOSITIONS FOR SELECTIVE DEGRADATION OF ENGINEERED PROTEINS | CELGENE CORPORATION (US) | 2024-08-15 | — | — | WO | disclosed |
| WO-2024081775-A1 | SYNTHESIS OF 6-FLUORO-2-METHYLBENZO[D]THIAZOL-5-YL COMPOUNDS | ELI LILLY AND COMPANY (US) | 2024-04-18 | — | — | WO | disclosed |
| US-20230192664-A1 | PYRIDAZINONES AS PARP7 INHIBITORS | ANKURA TRUST COMPANY, LLC, AS COLLATERAL TRUSTEE | 2023-06-22 | — | — | US | disclosed |
| US-11566020-B1 | Pyridazinones as PARP7 inhibitors | RIBON THERAPEUTICS, INC. (US) | 2023-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250034120-A1 | PYRIDAZINONES AS PARP7 INHIBITORS | PARP2, PARP1, PARP4 | CHRNB2 4647/4885CHRNA4 4310/4885HTR2C 1340/4885 |
| US-11566020-B1 | Pyridazinones as PARP7 inhibitors | PARP2, PARP1, PARP4 | CHRNB2 4647/4885CHRNA4 4310/4885HTR2C 1340/4885 |
| US-20230192664-A1 | PYRIDAZINONES AS PARP7 INHIBITORS | PARP2, PARP1, PARP4 | CHRNB2 4647/4885CHRNA4 4310/4885HTR2C 1340/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.