SCHEMBL30101835

SCHEMBL30101835

Fc1ccc(N2CCc3ccccc3C2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EED O75530 2/20 0.64
MEN1 O00255 3/20 0.59
KMT2A Q03164 3/20 0.59
MAOB P27338 2/20 0.58
MAPT P10636 2/20 0.49
KDM4E B2RXH2 1/20 0.49
ALDH1A1 P00352 1/20 0.49
POLB P06746 1/20 0.49
ALOX15 P16050 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
HSD17B10 Q99714 1/20 0.49
GRIN2D O15399 2/20 0.49
GRIN3B O60391 2/20 0.49
GRIN1 Q05586 2/20 0.49
GRIN2A Q12879 2/20 0.49
GRIN2B Q13224 2/20 0.49
GRIN2C Q14957 2/20 0.49
GRIN3A Q8TCU5 2/20 0.49
GAA P10253 1/20 0.48
NPC1 O15118 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10535865 1.00 EED (0.64) EEDMEN1KMT2AMAOBMAPT
SCHEMBL7611673 0.86 MEN1 (0.63) EEDMEN1KMT2AMAOBMAPT
SCHEMBL2600447 0.84 EED (0.72) EEDMEN1KMT2AMAOBMAPT
Hydrochloric Acid SCHEMBL10535845 0.82 EED (0.70) EEDMEN1KMT2AMAOBMAPT
SCHEMBL10534867 0.81 MEN1 (0.75) EEDMEN1KMT2AMAOBMAPT
SCHEMBL10534823 0.81 EED (0.64) EEDMEN1KMT2AGRIN2DGRIN3B
SCHEMBL8494183 0.81 EED (0.64) EEDMEN1KMT2AMAOBMAPT
SCHEMBL29836510 0.81 EED (0.64) EEDMEN1KMT2AMAOBMAPT
SCHEMBL29977823 0.81 EED (0.64) EEDMEN1KMT2AMAOBMAPT
SCHEMBL702928 0.81 EED (0.64) EEDMEN1KMT2AMAOBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118580187-A Preparation of dihydroisoquinoline method for preparing norone compounds 四川轻化工大学 2024-09-03 CN disclosed
CN-117946001-A Method for coupling near infrared photocatalysis 2-benzene-1, 2,3, 4-tetrahydroisoquinoline compound and nucleophile 陕西师范大学 2024-04-30 CN disclosed
CN-116462683-A N-condensed ring indole compound and preparation method thereof 常州大学 2023-07-21 CN disclosed
CN-113264881-B Synthetic method of alpha-cyanide 南昌大学 2022-12-02 CN disclosed