Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MKNK1 | Q9BUB5 | 5/20 | 0.47 |
| ▸ | MKNK2 | Q9HBH9 | 5/20 | 0.47 |
| ▸ | KMO | O15229 | 2/20 | 0.46 |
| ▸ | DHODH | Q02127 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NQO2 | P16083 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.44 |
| ▸ | EIF4E | P06730 | 1/20 | 0.43 |
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
| ▸ | KLK7 | P49862 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | ATR | Q13535 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23950565 | 1.00 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1MKNK1MKNK2KMO | |
| SCHEMBL23950751 | 0.90 | MKNK1 (0.56) | MKNK1MKNK2DHODHNQO2ADORA2A | |
| SCHEMBL30101922 | 0.86 | MAPK1 (0.52) | ALDH1A1MKNK1MKNK2KDM4ENQO2 | |
| SCHEMBL23390484 | 0.86 | MAPK1 (0.52) | ALDH1A1MKNK1MKNK2KDM4ENQO2 | |
| SCHEMBL25463116 | 0.83 | LMNA (0.51) | ALDH1A1L3MBTL1MKNK1MKNK2KMO | |
| SCHEMBL26295458 | 0.82 | P2RX7 (0.46) | KDM4EHTT | |
| SCHEMBL26295468 | 0.81 | MKNK1 (0.41) | ALDH1A1L3MBTL1MKNK1MKNK2KDM4E | |
| SCHEMBL26295471 | 0.79 | ACVR1B (0.46) | ALDH1A1KDM4EADORA2A | |
| SCHEMBL26295453 | 0.79 | ACVR1B (0.46) | ALDH1A1KDM4EADORA2A | |
| SCHEMBL25403249 | 0.77 | AHR (0.44) | ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115443276-B | Pyridopyrimidinone derivatives and their use as arene receptor modulators | 东亚ST株式会社 | 2025-04-18 | — | — | CN | disclosed |
| CN-115443276-A | Pyridopyrimidinone derivatives and their use as modulators of aromatic hydrocarbon receptors | 东亚ST株式会社 | 2022-12-06 | — | — | CN | disclosed |