SCHEMBL30101946

SCHEMBL30101946

c1ccc2c(c1)CCN(c1ccc3ccccc3c1)C2

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR3A P46098 2/20 0.57
EED O75530 2/20 0.56
S1PR5 Q9H228 1/20 0.55
HTR3E A5X5Y0 1/20 0.53
HTR3B O95264 1/20 0.53
HTR5A P47898 1/20 0.53
HTR3D Q70Z44 1/20 0.53
HTR3C Q8WXA8 1/20 0.53
SIGMAR1 Q99720 1/20 0.53
MEN1 O00255 1/20 0.53
KMT2A Q03164 1/20 0.53
GRIN2D O15399 7/20 0.50
GRIN3B O60391 7/20 0.50
GRIN1 Q05586 7/20 0.50
GRIN2A Q12879 7/20 0.50
GRIN2B Q13224 7/20 0.50
GRIN2C Q14957 7/20 0.50
GRIN3A Q8TCU5 7/20 0.50
IP6K1 Q92551 1/20 0.49
CHRM1 P11229 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28043610 1.00 HTR3A (0.57) HTR3AEEDS1PR5HTR3EHTR3B
SCHEMBL10536080 0.78 EED (0.54) EEDMEN1KMT2AGRIN2DGRIN3B
SCHEMBL29230002 0.78 EED (0.55) EEDMEN1KMT2AGRIN2DGRIN3B
SCHEMBL30874288 0.78 EED (0.55) EEDMEN1KMT2AGRIN2DGRIN3B
SCHEMBL2600447 0.77 EED (0.72) EEDMEN1KMT2AGRIN2DGRIN3B
SCHEMBL16453893 0.76 HTR3A (0.62) HTR3AEEDGRIN2DGRIN3BGRIN1
Hydrochloric Acid SCHEMBL10535845 0.76 EED (0.70) EEDMEN1KMT2AGRIN2DGRIN3B
SCHEMBL27806895 0.76 DRD1 (0.56) EED
SCHEMBL31070638 0.76 EED (0.51) EEDMEN1KMT2AGRIN2DGRIN3B
SCHEMBL26377274 0.76 EED (0.51) EEDMEN1KMT2AGRIN2DGRIN3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113264881-B Synthetic method of alpha-cyanide 南昌大学 2022-12-02 CN disclosed