Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 3/20 | 0.55 |
| ▸ | GRIN2D | O15399 | 5/20 | 0.54 |
| ▸ | GRIN3B | O60391 | 5/20 | 0.54 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.54 |
| ▸ | GRIN2A | Q12879 | 5/20 | 0.54 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.54 |
| ▸ | GRIN2C | Q14957 | 5/20 | 0.54 |
| ▸ | GRIN3A | Q8TCU5 | 5/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.54 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.54 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30874288 | 1.00 | EED (0.55) | EEDGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL29977823 | 0.81 | EED (0.64) | EEDGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL702928 | 0.81 | EED (0.64) | EEDGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL28454067 | 0.80 | GRIN2D (0.57) | EEDGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL29836323 | 0.80 | GRIN2D (0.57) | EEDGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL25774569 | 0.80 | GRIN2D (0.50) | EEDGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL10534812 | 0.79 | ALDH1A1 (0.76) | EEDGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL30101946 | 0.78 | HTR3A (0.57) | EEDGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL28043610 | 0.78 | HTR3A (0.57) | EEDGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL30296914 | 0.77 | EED (0.64) | EEDGRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117946001-A | Method for coupling near infrared photocatalysis 2-benzene-1, 2,3, 4-tetrahydroisoquinoline compound and nucleophile | 陕西师范大学 | 2024-04-30 | — | — | CN | disclosed |