Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 13/20 | 0.64 |
| ▸ | PDE4A | P27815 | 2/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1372747 | 1.00 | GPR119 (0.64) | GPR119PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3343638 | 0.91 | GPR119 (0.64) | GPR119PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5525265 | 0.90 | GPR119 (0.63) | GPR119PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7401143 | 0.89 | GPR119 (0.62) | GPR119PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL31044580 | 0.88 | GPR119 (0.50) | GPR119HRH3 | |
| SCHEMBL2776401 | 0.88 | GPR119 (0.62) | GPR119HRH3 | |
| SCHEMBL3346693 | 0.86 | GPR119 (0.62) | GPR119PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL31748202 | 0.86 | GPR119 (0.67) | GPR119NPBWR1MCHR1 | |
| SCHEMBL13993542 | 0.86 | GPR119 (0.67) | GPR119NPBWR1MCHR1 | |
| SCHEMBL3180265 | 0.85 | GPR119 (0.66) | GPR119NPBWR1MCHR1CHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110291085-B | Mutant isocitrate dehydrogenase inhibitors, compositions and methods thereof | 艾科生物科技有限公司 | 2023-01-24 | — | — | CN | disclosed |