Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV3 | Q8NET8 | 7/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.37 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.36 |
| ▸ | SYK | P43405 | 2/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23390164 | 1.00 | TRPV3 (0.38) | TRPV3PTGS1PTGS2HSP90AA1KDM5B | |
| SCHEMBL23390167 | 1.00 | TRPV3 (0.38) | TRPV3PTGS1PTGS2HSP90AA1KDM5B | |
| SCHEMBL23390273 | 0.93 | KDM5B (0.41) | TRPV3KDM5BSYK | |
| SCHEMBL23390274 | 0.93 | KDM5B (0.41) | TRPV3KDM5BSYK | |
| SCHEMBL23950679 | 0.92 | TRPV3 (0.41) | TRPV3PTGS1PTGS2HSP90AA1KDM5B | |
| SCHEMBL23390403 | 0.91 | TRPA1 (0.35) | TRPV3KDM5BTRPA1AHR | |
| SCHEMBL23390259 | 0.91 | EGLN1 (0.40) | TRPV3PTGS1PTGS2AHR | |
| SCHEMBL30101937 | 0.91 | EGLN1 (0.40) | TRPV3PTGS1PTGS2AHR | |
| SCHEMBL23390257 | 0.91 | EGLN1 (0.40) | TRPV3PTGS1PTGS2AHR | |
| SCHEMBL23390485 | 0.91 | TRPV3 (0.38) | TRPV3KDM5BTRPA1SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115443276-B | Pyridopyrimidinone derivatives and their use as arene receptor modulators | 东亚ST株式会社 | 2025-04-18 | — | — | CN | claimed |
| CN-115443276-B | Pyridopyrimidinone derivatives and their use as arene receptor modulators | 东亚ST株式会社 | 2025-04-18 | — | — | CN | disclosed |
| CN-115443276-A | Pyridopyrimidinone derivatives and their use as modulators of aromatic hydrocarbon receptors | 东亚ST株式会社 | 2022-12-06 | — | — | CN | disclosed |