Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 2/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.39 |
| ▸ | AOC1 | P19801 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ASPH | Q12797 | 1/20 | 0.38 |
| ▸ | RIOX2 | Q8IUF8 | 1/20 | 0.38 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.38 |
| ▸ | CD38 | P28907 | 1/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30102415 | 0.81 | ACHE (0.33) | PTGER4AAK1ALOX15TAS1R3TAS1R1 | |
| SCHEMBL8885032 | 0.74 | PTGER4 (0.43) | PTGER4KDM4CAOC1AOC3KDM4E | |
| SCHEMBL27925730 | 0.70 | KMT2A (0.52) | KDM4CAOC1AOC3CD38ALDH1A1 | |
| SCHEMBL6608117 | 0.69 | PTGER4 (0.47) | PTGER4KDM4CKDM4EASPHRIOX2 | |
| SCHEMBL2950591 | 0.68 | AAK1 (0.62) | PTGER4KDM4CAOC1AOC3KDM4E | |
| SCHEMBL1528478 | 0.68 | AAK1 (0.51) | PTGER4KDM4CAOC1AOC3KDM4E | |
| SCHEMBL13493867 | 0.68 | APP (0.39) | PTGER4AOC1AOC3NPC1RAB9A | |
| SCHEMBL10368992 | 0.68 | GAA (0.50) | KDM4ENPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL3930758 | 0.68 | PTGER4 (0.51) | PTGER4KDM4CKDM4EASPHRIOX2 | |
| SCHEMBL7470752 | 0.67 | CD44 (0.48) | NPC1ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272313-A1 | MODULATORS OF HISTONE ACETYLTRANSFERASE 1 AND METHODS OF TREATMENT THEREOF | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2022-12-29 | — | — | WO | disclosed |