Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.44 |
| ▸ | DRD4 | P21917 | 7/20 | 0.44 |
| ▸ | DRD3 | P35462 | 7/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30102414 | 0.74 | PTGER4 (0.33) | L3MBTL1ALDH1A1MAPTPTGER4 | |
| SCHEMBL30102413 | 0.74 | HAT1 (0.36) | L3MBTL1ALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL30102484 | 0.74 | KDM4E (0.37) | DRD4ALDH1A1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL30102408 | 0.72 | KCNQ2 (0.36) | L3MBTL1ALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL12288186 | 0.70 | HDAC6 (0.59) | DRD2DRD4DRD3ALDH1A1TP53 | |
| SCHEMBL30102415 | 0.70 | ACHE (0.33) | PTGER4 | |
| SCHEMBL17487505 | 0.68 | DRD4 (0.44) | DRD2DRD4DRD3ALDH1A1HPGD | |
| SCHEMBL29848341 | 0.66 | MAPT (0.50) | L3MBTL1ALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL29093415 | 0.65 | GALR3 (0.67) | DRD2DRD4DRD3L3MBTL1ALDH1A1 | |
| SCHEMBL30575444 | 0.65 | GALR3 (0.67) | DRD2DRD4DRD3L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272313-A1 | MODULATORS OF HISTONE ACETYLTRANSFERASE 1 AND METHODS OF TREATMENT THEREOF | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2022-12-29 | — | — | WO | disclosed |