Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30102413 | 0.82 | HAT1 (0.36) | PTGER4ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL30102484 | 0.79 | KDM4E (0.37) | PTGER4ALDH1A1MAPT | |
| SCHEMBL30102408 | 0.77 | KCNQ2 (0.36) | PTGER4ALDH1A1L3MBTL1 | |
| SCHEMBL30102415 | 0.77 | ACHE (0.33) | PTGER4 | |
| SCHEMBL30102431 | 0.74 | DRD2 (0.44) | PTGER4ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL7470752 | 0.65 | CD44 (0.48) | ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL30102382 | 0.65 | HDAC8 (0.46) | L3MBTL1 | |
| SCHEMBL30102420 | 0.65 | PTGER4 (0.41) | PTGER4ALDH1A1 | |
| SCHEMBL10948580 | 0.64 | GAA (0.57) | ALDH1A1 | |
| SCHEMBL10368992 | 0.63 | GAA (0.50) | ALDH1A1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272313-A1 | MODULATORS OF HISTONE ACETYLTRANSFERASE 1 AND METHODS OF TREATMENT THEREOF | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2022-12-29 | — | — | WO | disclosed |