Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | GABRP | O00591 | 1/20 | 0.55 |
| ▸ | GABRD | O14764 | 1/20 | 0.55 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.55 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.55 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.55 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.55 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.55 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.55 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.55 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.55 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.55 |
| ▸ | GABRE | P78334 | 1/20 | 0.55 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.55 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.55 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.55 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL148900 | 1.00 | LMNA (0.55) | LMNAGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL6216533 | 0.87 | GABRP (0.53) | LMNAGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL27656222 | 0.87 | LMNA (0.56) | LMNARAB9ANPC1GAA | |
| SCHEMBL4195397 | 0.85 | LMNA (0.58) | LMNARAB9ANPC1GAASMN1; SMN2 | |
| SCHEMBL16418609 | 0.85 | GABRP (0.58) | LMNAGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL3550940 | 0.84 | LMNA (0.54) | LMNAGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL30572236 | 0.84 | LMNA (0.54) | LMNAGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL192851 | 0.84 | LMNA (0.54) | LMNARAB9ANPC1GAA | |
| SCHEMBL4198423 | 0.82 | LMNA (0.56) | LMNARAB9ANPC1GAAALDH1A1 | |
| SCHEMBL4480620 | 0.81 | TAS2R14 (0.46) | LMNARAB9ANPC1GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115443129-A | KCNT1 inhibitors and methods of use | 普拉西斯精密医药公司 | 2022-12-06 | — | — | CN | disclosed |