Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GCGR | P47871 | 2/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 5/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | KLK7 | P49862 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24784548 | 1.00 | MCHR1 (0.39) | MCHR1HPGDSCNR2MEN1KMT2A | |
| SCHEMBL30103065 | 0.92 | IDH1 (0.37) | MCHR1HPGDSMEN1KMT2AROCK2 | |
| SCHEMBL30103101 | 0.91 | CRHR1 (0.37) | MCHR1CNR2ROCK2CNR1CRHR1 | |
| SCHEMBL30103091 | 0.91 | CRHR1 (0.37) | MCHR1CNR2ROCK2CNR1CRHR1 | |
| SCHEMBL24785453 | 0.91 | CRHR1 (0.37) | MCHR1CNR2ROCK2CNR1CRHR1 | |
| SCHEMBL24784610 | 0.91 | MCHR1 (0.43) | MCHR1CNR2MEN1KMT2AGCGR | |
| SCHEMBL24785350 | 0.90 | MCHR1 (0.37) | MCHR1CNR2ROCK2CRHR1CRHR2 | |
| SCHEMBL30018547 | 0.90 | MCHR1 (0.37) | MCHR1CNR2ROCK2CRHR1CRHR2 | |
| SCHEMBL24785852 | 0.90 | MCHR1 (0.34) | MCHR1HPGDSCNR2ROCK2CNR1 | |
| SCHEMBL30017941 | 0.90 | MCHR1 (0.34) | MCHR1HPGDSCNR2ROCK2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115448913-A | Bicyclic compounds for the treatment of EP2, EP4 receptor mediated diseases | 武汉人福创新药物研发中心有限公司 | 2022-12-09 | — | — | CN | disclosed |