Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.36 |
| ▸ | PTGIR | P43119 | 1/20 | 0.35 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.35 |
| ▸ | HPGDS | O60760 | 2/20 | 0.35 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | DRD5 | P21918 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24784548 | 0.92 | MCHR1 (0.39) | MCHR1HPGDSROCK2MEN1KMT2A | |
| SCHEMBL30103049 | 0.92 | MCHR1 (0.39) | MCHR1HPGDSROCK2MEN1KMT2A | |
| SCHEMBL24784585 | 0.91 | IDH1 (0.41) | IDH1MCHR1PTGIRPTGDRHPGDS | |
| SCHEMBL24785453 | 0.91 | CRHR1 (0.37) | IDH1MCHR1ROCK2 | |
| SCHEMBL30103101 | 0.91 | CRHR1 (0.37) | IDH1MCHR1ROCK2 | |
| SCHEMBL30103091 | 0.91 | CRHR1 (0.37) | IDH1MCHR1ROCK2 | |
| SCHEMBL24785852 | 0.90 | MCHR1 (0.34) | MCHR1HPGDSROCK2FFAR4 | |
| SCHEMBL30017941 | 0.90 | MCHR1 (0.34) | MCHR1HPGDSROCK2FFAR4 | |
| SCHEMBL30018138 | 0.89 | HPGDS (0.34) | MCHR1HPGDSDRD4ROCK2HDAC1 | |
| SCHEMBL30017729 | 0.89 | ROCK2 (0.35) | MCHR1ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115448913-A | Bicyclic compounds for the treatment of EP2, EP4 receptor mediated diseases | 武汉人福创新药物研发中心有限公司 | 2022-12-09 | — | — | CN | disclosed |