Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 3/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 4/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.33 |
| ▸ | CNR1 | P21554 | 3/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | CCR3 | P51677 | 2/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.33 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24785453 | 1.00 | CRHR1 (0.37) | CRHR1CRHR2CNR2ROCK2CNR1 | |
| SCHEMBL30103101 | 1.00 | CRHR1 (0.37) | CRHR1CRHR2CNR2ROCK2CNR1 | |
| SCHEMBL21458211 | 0.92 | CRHR1 (0.37) | CRHR1CRHR2CNR2CNR1PTGER4 | |
| SCHEMBL31203506 | 0.92 | CRHR1 (0.37) | CRHR1CRHR2CNR2CNR1PTGER4 | |
| SCHEMBL30103049 | 0.91 | MCHR1 (0.39) | CRHR1CRHR2CNR2ROCK2CNR1 | |
| SCHEMBL24784548 | 0.91 | MCHR1 (0.39) | CRHR1CRHR2CNR2ROCK2CNR1 | |
| SCHEMBL30017918 | 0.91 | CRHR1 (0.39) | CRHR1CRHR2CNR2CNR1PTGER4 | |
| SCHEMBL30103065 | 0.91 | IDH1 (0.37) | ROCK2IDH1MCHR1 | |
| SCHEMBL24784544 | 0.90 | CRHR1 (0.45) | CRHR1CRHR2CNR2CNR1IDH1 | |
| SCHEMBL30018128 | 0.90 | CNR2 (0.41) | CRHR1CRHR2CNR2CNR1CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115448913-A | Bicyclic compounds for the treatment of EP2, EP4 receptor mediated diseases | 武汉人福创新药物研发中心有限公司 | 2022-12-09 | — | — | CN | disclosed |