Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | KMO | O15229 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.41 |
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 4/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30103014 | 0.85 | GRM2 (0.53) | RECQLKMOLMNASMN1; SMN2CYP11B1 | |
| SCHEMBL30018748 | 0.84 | GRIN1 (0.44) | KMOADORA3ADORA1GRIN1GRIN2B | |
| SCHEMBL9917342 | 0.80 | KMO (0.57) | RECQLKMOGRIN1GRIN2BHDAC8 | |
| SCHEMBL30018361 | 0.79 | QPCT (0.47) | KMOGRIN1GRIN2BERBB2GAA | |
| SCHEMBL30018366 | 0.78 | GRIN1 (0.41) | KMOCYP11B1GRIN1GRIN2BERBB2 | |
| SCHEMBL30103077 | 0.78 | KMO (0.47) | RECQLKMOLMNASMN1; SMN2CYP11B1 | |
| SCHEMBL24785451 | 0.76 | MEN1 (0.43) | RECQLLMNASMN1; SMN2NR1H3NR1H2 | |
| SCHEMBL30018739 | 0.76 | MEN1 (0.43) | RECQLLMNASMN1; SMN2NR1H3NR1H2 | |
| SCHEMBL30103018 | 0.75 | KMO (0.47) | RECQLKMOCYP11B1SCN9AADORA3 | |
| SCHEMBL24785446 | 0.72 | KMT2A (0.40) | LMNASMN1; SMN2ERBB2EGFRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115448913-A | Bicyclic compounds for the treatment of EP2, EP4 receptor mediated diseases | 武汉人福创新药物研发中心有限公司 | 2022-12-09 | — | — | CN | disclosed |