Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.64 |
| ▸ | RAB9A | P51151 | 8/20 | 0.64 |
| ▸ | NPC1 | O15118 | 7/20 | 0.64 |
| ▸ | TP53 | P04637 | 2/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16440913 | 0.91 | CASP3 (0.64) | SMN1; SMN2RAB9ANPC1TP53PKM | |
| SCHEMBL10685389 | 0.90 | CASP3 (0.63) | SMN1; SMN2RAB9ANPC1TP53PKM | |
| SCHEMBL9806791 | 0.90 | CASP3 (0.63) | SMN1; SMN2RAB9ANPC1TP53PKM | |
| SCHEMBL9815145 | 0.90 | CASP3 (0.63) | SMN1; SMN2RAB9ANPC1TP53PKM | |
| SCHEMBL9806787 | 0.90 | CASP3 (0.63) | SMN1; SMN2RAB9ANPC1TP53PKM | |
| SCHEMBL9806842 | 0.90 | CASP3 (0.63) | SMN1; SMN2RAB9ANPC1TP53PKM | |
| SCHEMBL9806783 | 0.87 | SMN1; SMN2 (0.61) | SMN1; SMN2RAB9ANPC1TP53PKM | |
| SCHEMBL24785848 | 0.85 | CYP17A1 (0.50) | SMN1; SMN2RAB9ANPC1TP53PKM | |
| SCHEMBL30103064 | 0.85 | CYP17A1 (0.50) | SMN1; SMN2RAB9ANPC1TP53PKM | |
| SCHEMBL30103108 | 0.85 | CYP17A1 (0.50) | SMN1; SMN2RAB9ANPC1TP53PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0244939-B1 | HALOGEN-CONTAINING PYRIDINE COMPOUND AND LIQUID CRYSTAL COMPOSITION | Chisso Corporation (JP) | 1991-04-24 | — | — | EP | disclosed |
| US-4781857-A | SWITCHES, FERROELECTRICITY | CHISSO CORPORATION (JP) | 1988-11-01 | — | — | US | disclosed |
| EP-0244939-A1 | Halogen-containing pyridine compound and liquid crystal composition | Chisso Corporation (JP) | 1987-11-11 | — | — | EP | disclosed |