Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.37 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24785446 | 1.00 | KMT2A (0.40) | KMT2AMEN1SMN1; SMN2CNR1CYP1A2 | |
| SCHEMBL24784564 | 0.90 | NPBWR1 (0.41) | KMT2AMEN1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL30103029 | 0.90 | NPBWR1 (0.41) | KMT2AMEN1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL30843297 | 0.90 | NPBWR1 (0.44) | KMT2AMEN1SMN1; SMN2CNR1CYP1A2 | |
| SCHEMBL21458333 | 0.90 | NPBWR1 (0.44) | KMT2AMEN1SMN1; SMN2CNR1CYP1A2 | |
| SCHEMBL24785074 | 0.90 | NR1H2 (0.42) | KMT2AMEN1SMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL30103084 | 0.90 | NR1H2 (0.42) | KMT2AMEN1SMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL24785451 | 0.89 | MEN1 (0.43) | KMT2AMEN1SMN1; SMN2POLBKDM4E | |
| SCHEMBL30018739 | 0.89 | MEN1 (0.43) | KMT2AMEN1SMN1; SMN2POLBKDM4E | |
| SCHEMBL24784529 | 0.88 | KMT2A (0.45) | KMT2AMEN1SMN1; SMN2CNR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115448913-A | Bicyclic compounds for the treatment of EP2, EP4 receptor mediated diseases | 武汉人福创新药物研发中心有限公司 | 2022-12-09 | — | — | CN | disclosed |