Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 7/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.38 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.38 |
| ▸ | GCGR | P47871 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24784564 | 1.00 | NPBWR1 (0.41) | NPBWR1PLA2G2AKDM4ECYP1A2CYP2D6 | |
| SCHEMBL24784545 | 0.91 | NPBWR1 (0.41) | NPBWR1KDM4EMEN1KMT2AGCGR | |
| SCHEMBL30103058 | 0.91 | NPBWR1 (0.41) | NPBWR1KDM4EMEN1KMT2AGCGR | |
| SCHEMBL30103067 | 0.90 | KMT2A (0.40) | NPBWR1PLA2G2AKDM4ECYP1A2CYP2C9 | |
| SCHEMBL24785446 | 0.90 | KMT2A (0.40) | NPBWR1PLA2G2AKDM4ECYP1A2CYP2C9 | |
| SCHEMBL24785074 | 0.90 | NR1H2 (0.42) | NPBWR1KDM4ECYP1A2CYP2C9CYP2C19 | |
| SCHEMBL30103084 | 0.90 | NR1H2 (0.42) | NPBWR1KDM4ECYP1A2CYP2C9CYP2C19 | |
| SCHEMBL24784614 | 0.87 | P2RX7 (0.39) | NPBWR1KMT2A | |
| SCHEMBL24785079 | 0.87 | CACNA1H (0.40) | BRD4 | |
| SCHEMBL30103053 | 0.87 | P2RX7 (0.39) | NPBWR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115448913-A | Bicyclic compounds for the treatment of EP2, EP4 receptor mediated diseases | 武汉人福创新药物研发中心有限公司 | 2022-12-09 | — | — | CN | disclosed |