Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | FOS | P01100 | 1/20 | 0.40 |
| ▸ | JUN | P05412 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24785074 | 1.00 | NR1H2 (0.42) | NR1H2NR1H3METHDAC1HDAC6 | |
| SCHEMBL24785096 | 0.92 | KMT2A (0.47) | NR1H2NR1H3METHDAC1HDAC6 | |
| SCHEMBL30103052 | 0.92 | KMT2A (0.47) | NR1H2NR1H3METHDAC1HDAC6 | |
| SCHEMBL30103029 | 0.90 | NPBWR1 (0.41) | KMT2AKDM4EMEN1CYP1A2CYP2C9 | |
| SCHEMBL24784564 | 0.90 | NPBWR1 (0.41) | KMT2AKDM4EMEN1CYP1A2CYP2C9 | |
| SCHEMBL24785446 | 0.90 | KMT2A (0.40) | KMT2ASMN1; SMN2KDM4EALDH1A1LMNA | |
| SCHEMBL30103067 | 0.90 | KMT2A (0.40) | KMT2ASMN1; SMN2KDM4EALDH1A1LMNA | |
| SCHEMBL24784614 | 0.86 | P2RX7 (0.39) | METKMT2ASMN1; SMN2RAB9AGRIN1 | |
| SCHEMBL30103053 | 0.86 | P2RX7 (0.39) | METKMT2ASMN1; SMN2RAB9AGRIN1 | |
| SCHEMBL24784639 | 0.85 | MDM2 (0.34) | METRAB9ANPBWR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115448913-A | Bicyclic compounds for the treatment of EP2, EP4 receptor mediated diseases | 武汉人福创新药物研发中心有限公司 | 2022-12-09 | — | — | CN | disclosed |