Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.46 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24785814 | 1.00 | ALDH1A1 (0.47) | ALDH1A1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL24785826 | 0.89 | KDM1A (0.49) | ALDH1A1PDGFRBPDGFRAKDM4EPTGS2 | |
| SCHEMBL30103062 | 0.89 | KDM1A (0.49) | ALDH1A1PDGFRBPDGFRAKDM4EPTGS2 | |
| SCHEMBL24785816 | 0.86 | NPC1 (0.47) | ALDH1A1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL30103021 | 0.86 | NPC1 (0.47) | ALDH1A1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL12987006 | 0.75 | ALDH1A1 (0.50) | ALDH1A1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL24785829 | 0.75 | KDM1A (0.49) | PDGFRBPDGFRAPTGS2ALOX5APFEN1 | |
| SCHEMBL30103087 | 0.75 | KDM1A (0.49) | PDGFRBPDGFRAPTGS2ALOX5APFEN1 | |
| SCHEMBL12987609 | 0.75 | ALDH1A1 (0.52) | ALDH1A1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL24667671 | 0.74 | PDGFRB (0.36) | ALDH1A1PDGFRBPDGFRACYP17A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115448913-A | Bicyclic compounds for the treatment of EP2, EP4 receptor mediated diseases | 武汉人福创新药物研发中心有限公司 | 2022-12-09 | — | — | CN | disclosed |