Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 2/20 | 0.46 |
| ▸ | IDO2 | Q6ZQW0 | 2/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.43 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.43 |
| ▸ | MAT2A | P31153 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.41 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | PI4KA | P42356 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24111048 | 1.00 | TDO2 (0.46) | TDO2IDO2PIK3CDPIK3CGPIK3C3 | |
| SCHEMBL24110965 | 0.91 | POLB (0.49) | TDO2IDO2PIK3CDPIK3CGPIK3C3 | |
| SCHEMBL23958125 | 0.91 | MAT2A (0.47) | TDO2IDO2PIK3CDPIK3CGPIK3C3 | |
| SCHEMBL23958159 | 0.88 | HTR7 (0.45) | TDO2IDO2PIK3CDPIK3CGPIK3C3 | |
| SCHEMBL30103197 | 0.88 | PIK3CB (0.47) | TDO2IDO2PIK3CDPIK3CGPIK3C3 | |
| SCHEMBL24110790 | 0.88 | PIK3CB (0.47) | TDO2IDO2PIK3CDPIK3CGPIK3C3 | |
| SCHEMBL24111012 | 0.87 | BTK (0.50) | TDO2IDO2PIK3CDPIK3CGPIK3C3 | |
| SCHEMBL23958178 | 0.85 | PIK3CD (0.43) | TDO2IDO2PIK3CDPIK3CGPIK3C3 | |
| SCHEMBL23958177 | 0.84 | TDO2 (0.44) | TDO2IDO2PIK3CDPIK3CGPIK3C3 | |
| SCHEMBL23931388 | 0.84 | TDO2 (0.44) | TDO2IDO2PIK3CDPIK3CGPIK3C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115427399-A | 2-heteroarylaminoquinazolinone derivatives | 住友制药株式会社 | 2022-12-02 | — | — | CN | claimed |
| CN-115427399-A | 2-heteroarylaminoquinazolinone derivatives | 住友制药株式会社 | 2022-12-02 | — | — | CN | disclosed |