Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | MLYCD | O95822 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14343054 | 0.91 | EPHX2 (0.38) | CHRM2CHRM1CHRM3EPHX2NR1H2 | |
| SCHEMBL31034456 | 0.85 | CHRM2 (0.36) | CHRM2CHRM1CHRM3EPHX2 | |
| SCHEMBL30103403 | 0.85 | TSHR (0.39) | EPHX2NR1H2MLYCD | |
| SCHEMBL26351173 | 0.83 | EPHX2 (0.35) | EPHX2NR1H2 | |
| SCHEMBL20722075 | 0.82 | CHRM2 (0.42) | CHRM2CHRM1CHRM3EPHX2NR1H2 | |
| SCHEMBL22616385 | 0.82 | CHRM2 (0.42) | CHRM2CHRM1CHRM3EPHX2NR1H2 | |
| SCHEMBL20722074 | 0.82 | CHRM2 (0.42) | CHRM2CHRM1CHRM3EPHX2NR1H2 | |
| SCHEMBL14533784 | 0.81 | NAAA (0.38) | CHRM2CHRM1CHRM3EPHX2 | |
| SCHEMBL25030467 | 0.79 | NAAA (0.39) | EPHX2 | |
| SCHEMBL23295591 | 0.79 | EPHX2 (0.36) | EPHX2MLYCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4097138-A1 | ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS | Avila Therapeutics, Inc. (US) | 2022-12-07 | — | — | EP | disclosed |