Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 4/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | MLYCD | O95822 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14343054 | 0.93 | EPHX2 (0.38) | EPHX2MLYCDSTING1NR1H2 | |
| SCHEMBL30103387 | 0.85 | CHRM2 (0.40) | EPHX2MLYCDNR1H2 | |
| SCHEMBL30103398 | 0.84 | EPHX2 (0.31) | EPHX2 | |
| SCHEMBL23696855 | 0.83 | BTK (0.43) | TSHREPHX2CA12CA14CA2 | |
| SCHEMBL21996967 | 0.83 | BTK (0.43) | TSHREPHX2CA12CA14CA2 | |
| SCHEMBL26351173 | 0.82 | EPHX2 (0.35) | EPHX2NR1H2 | |
| SCHEMBL29868442 | 0.81 | TSHR (0.48) | TSHREPHX2CA12CA14CA2 | |
| SCHEMBL26880031 | 0.81 | TSHR (0.43) | TSHREPHX2CA12CA14CA2 | |
| SCHEMBL26880038 | 0.81 | TSHR (0.48) | TSHREPHX2CA12CA14CA2 | |
| SCHEMBL14533784 | 0.79 | NAAA (0.38) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4097138-A1 | ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS | Avila Therapeutics, Inc. (US) | 2022-12-07 | — | — | EP | disclosed |