Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | IDUA | P35475 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20952821 | 0.93 | MEN1 (0.52) | FAAHMEN1MAPK1KMT2ACNR2 | |
| SCHEMBL22355749 | 0.84 | FAAH (0.44) | FAAHMEN1MAPK1KMT2ACNR2 | |
| SCHEMBL15791255 | 0.83 | CNR2 (0.41) | FAAHMEN1MAPK1KMT2ACNR2 | |
| SCHEMBL25552526 | 0.81 | DNM1 (0.39) | FAAHMEN1MAPK1KMT2ACNR2 | |
| SCHEMBL12934930 | 0.81 | FAAH (0.83) | FAAHMEN1MAPK1KMT2AEPHX2 | |
| SCHEMBL12934924 | 0.81 | FAAH (0.83) | FAAHMEN1MAPK1KMT2AEPHX2 | |
| SCHEMBL12934928 | 0.81 | FAAH (0.83) | FAAHMEN1MAPK1KMT2AEPHX2 | |
| SCHEMBL30218382 | 0.81 | EPHX2 (0.44) | FAAHMEN1MAPK1KMT2ACNR2 | |
| SCHEMBL25839733 | 0.81 | MEN1 (0.40) | FAAHMEN1MAPK1KMT2ACNR2 | |
| SCHEMBL19079656 | 0.80 | CNR2 (0.42) | FAAHMEN1MAPK1KMT2ACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4097138-A1 | ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS | Avila Therapeutics, Inc. (US) | 2022-12-07 | — | — | EP | disclosed |