SCHEMBL19079656

SCHEMBL19079656

CNC(=O)CCCCCN=[N+]=[N-]

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 1/20 0.42
LMNA P02545 1/20 0.38
HDAC8 Q9BY41 4/20 0.37
HDAC2 Q92769 3/20 0.37
HDAC3 O15379 2/20 0.37
HDAC1 Q13547 2/20 0.37
HDAC6 Q9UBN7 2/20 0.37
HDAC5 Q9UQL6 2/20 0.37
HSP90AA1 P07900 1/20 0.35
IDUA P35475 1/20 0.35
FAAH O00519 2/20 0.34
NAMPT P43490 1/20 0.34
POLB P06746 1/20 0.33
ALOX5 P09917 1/20 0.33
MEN1 O00255 1/20 0.32
MAPK1 P28482 1/20 0.32
KMT2A Q03164 1/20 0.32
TBXAS1 P24557 1/20 0.32
HDAC4 P56524 1/20 0.32
HDAC7 Q8WUI4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25026065 0.98 CNR2 (0.40) CNR2LMNAHDAC8HDAC2HDAC3
SCHEMBL15581632 0.92 LMNA (0.40) CNR2LMNAHDAC8HDAC2HDAC3
SCHEMBL18510218 0.84
SCHEMBL18925537 0.84
SCHEMBL14328132 0.82 HDAC8 (0.60) HDAC8HDAC2HDAC3HDAC1HDAC6
SCHEMBL14129575 0.81 ALDH1A1 (0.47) CNR2LMNAHDAC8HDAC2HDAC3
SCHEMBL18019146 0.81 ALDH1A1 (0.47) CNR2LMNAHDAC8HDAC2HDAC3
SCHEMBL30103426 0.80 FAAH (0.58) CNR2IDUAFAAHMEN1MAPK1
SCHEMBL26869086 0.79 CNR2 (0.34) CNR2LMNAPOLBALOX5
SCHEMBL13651623 0.79 FAAH (0.49) FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240026421-A1 METHODS FOR CAPTURING LONG POLYNUCLEOTIDES FOR SEQUENCING SPECIFIC GENOMIC REGIONS GENERATION BIOTECH, LLC (US) 2024-01-25 US disclosed
US-20240026421-A1 METHODS FOR CAPTURING LONG POLYNUCLEOTIDES FOR SEQUENCING SPECIFIC GENOMIC REGIONS GENERATION BIOTECH, LLC (US) 2024-01-25 US disclosed
US-11821023-B2 Method for capturing long polynucleotides for sequencing specific gnomic regions GENERATION BIOTECH, LLC (US) 2023-11-21 US disclosed
US-11821023-B2 Method for capturing long polynucleotides for sequencing specific gnomic regions GENERATION BIOTECH, LLC (US) 2023-11-21 US disclosed
EP-3812376-A1 PACLITAXEL-LIPID-POLYSACCHARIDE DUAL-TYPE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF Santolecan Pharmaceuticals LLC (US) 2021-04-28 EP disclosed
WO-2020160230-A1 CHEMICAL REPORTER PROBES, KITS, AND METHODS OF USING THE SAME ARTRIS THERAPEUTICS INC. (US) 2020-08-06 WO disclosed
US-20170190983-A1 PROCESS OF CONVERTING NATURAL PLANT OILS TO BIOFUELS UNITED STATES DEPARTMENT OF ENERGY 2017-07-06 US disclosed