Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP2 | O95551 | 2/20 | 0.40 |
| ▸ | PLK1 | P53350 | 2/20 | 0.39 |
| ▸ | P4HA1 | P13674 | 3/20 | 0.39 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 4/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19648301 | 0.85 | HTT (0.41) | HTTPLK1P4HA1P4HTMGSK3B | |
| SCHEMBL15147661 | 0.81 | ALDH1A1 (0.47) | HTTGSK3BDDB1CRBNALDH1A1 | |
| SCHEMBL24897446 | 0.79 | KDM4E (0.49) | HTTP4HTMHCAR3ALDH1A1 | |
| SCHEMBL18940450 | 0.76 | CYP11B1 (0.35) | HTTP4HA1P4HTMHCAR3MIF | |
| SCHEMBL24306267 | 0.75 | OTUD7B (0.36) | HTTP4HA1P4HTMHCAR3DDB1 | |
| SCHEMBL24897390 | 0.75 | HPGD (0.43) | HTTCRBNHPGDMGLL | |
| SCHEMBL11662986 | 0.74 | HTT (0.40) | HTTP4HA1P4HTMGSK3BGSK3A | |
| SCHEMBL24897467 | 0.74 | SMYD3 (0.67) | — | |
| SCHEMBL658962 | 0.74 | AHR (0.53) | PLK1GSK3BGSK3ACDK5CDK5R1 | |
| SCHEMBL13617978 | 0.74 | AHR (0.37) | GSK3BGSK3ACDK5CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4061373-A1 | METHODS FOR TREATING INFLAMMATORY BOWEL DISEASE | Angion Biomedica Corp. (US) | 2022-09-28 | — | — | EP | disclosed |