Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.58 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | FBP1 | P09467 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.48 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.47 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | RET | P07949 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3010462 | 1.00 | ALDH1A1 (0.63) | ALDH1A1CYP1A2CYP2C19MTNR1AMTNR1B | |
| SCHEMBL2536634 | 0.89 | MAPT (0.63) | ALDH1A1CYP1A2CYP2C19MTNR1AMTNR1B | |
| SCHEMBL2536633 | 0.89 | MAPT (0.63) | ALDH1A1CYP1A2CYP2C19MTNR1AMTNR1B | |
| SCHEMBL29637948 | 0.89 | MAPT (0.63) | ALDH1A1CYP1A2CYP2C19MTNR1AMTNR1B | |
| SCHEMBL17490947 | 0.85 | TLR4 (0.55) | ALDH1A1CYP1A2CYP2C19MTNR1AMTNR1B | |
| SCHEMBL2537801 | 0.83 | ALDH1A1 (0.43) | ALDH1A1CYP1A2CYP2C19MTNR1AMTNR1B | |
| SCHEMBL2537799 | 0.83 | ALDH1A1 (0.43) | ALDH1A1CYP1A2CYP2C19MTNR1AMTNR1B | |
| SCHEMBL17488523 | 0.82 | MEN1 (0.52) | ALDH1A1CYP1A2CYP2C19MTNR1AMTNR1B | |
| SCHEMBL8404322 | 0.82 | MEN1 (0.52) | ALDH1A1CYP1A2CYP2C19MTNR1AMTNR1B | |
| SCHEMBL13947142 | 0.80 | ALDH1A1 (0.69) | ALDH1A1CYP1A2CYP2C19MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114680114-B | Application of melatonin derivative in preventing and treating plant fungal diseases | 华中农业大学 | 2022-11-15 | — | — | CN | disclosed |
| CN-114680114-A | Application of melatonin derivative in preventing and treating plant fungal diseases | 华中农业大学 | 2022-07-01 | — | — | CN | disclosed |
| US-8258173-B2 | Melatonin derivatives and their use as antioxidants | UNIVERSITY OF SUNDERLAND (GB) | 2012-09-04 | — | — | US | disclosed |
| US-20100204276-A1 | INDOLE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LES LABORATOIRES SERVIER (FR) | 2010-08-12 | — | — | US | disclosed |
| US-20100063125-A1 | MELATONIN DERIVATIVES AND THEIR USE AS ANTIOXIDANTS | UNIVERSITY OF SUNDERLAND (GB) | 2010-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100063125-A1 | MELATONIN DERIVATIVES AND THEIR USE AS ANTIOXIDANTS | MTNR1A, MTNR1B, TXNRD2 | ALDH1A1 250/4885CYP1A2 217/4885CYP2C19 419/4885 |
| US-20100204276-A1 | INDOLE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MTNR1A, MTNR1B, IDO1 | ALDH1A1 727/4885CYP1A2 73/4885CYP2C19 81/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.