Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 10/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.62 |
| ▸ | ADRB2 | P07550 | 8/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.62 |
| ▸ | TSHR | P16473 | 6/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.62 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.62 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.62 |
| ▸ | RECQL | P46063 | 4/20 | 0.62 |
| ▸ | MTOR | P42345 | 3/20 | 0.62 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.62 |
| ▸ | DRD2 | P14416 | 3/20 | 0.62 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.62 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3442521 | 1.00 | MAPT (0.62) | MAPTTDP1KDM4EADRB2HSD17B10 | |
| SCHEMBL12610450 | 0.85 | MAPT (0.49) | MAPTTDP1KDM4EADRB2HSD17B10 | |
| SCHEMBL31530706 | 0.80 | ADRB2 (0.68) | MAPTTDP1KDM4EADRB2HSD17B10 | |
| SCHEMBL3443638 | 0.80 | HIF1A (0.58) | TDP1KDM4EADRB2HSD17B10TSHR | |
| SCHEMBL28528503 | 0.80 | MAPT (0.58) | MAPTTDP1KDM4EADRB2HSD17B10 | |
| SCHEMBL31530707 | 0.80 | ADRB2 (0.68) | MAPTTDP1KDM4EADRB2HSD17B10 | |
| SCHEMBL28151492 | 0.79 | ADRB2 (0.66) | MAPTTDP1KDM4EADRB2HSD17B10 | |
| SCHEMBL3442803 | 0.78 | HIF1A (0.64) | KDM4EADRB2TSHRADRB1MEN1 | |
| SCHEMBL25100811 | 0.77 | MAPT (0.69) | MAPTTDP1KDM4EADRB2HSD17B10 | |
| SCHEMBL9768173 | 0.77 | MAPT (0.69) | MAPTTDP1KDM4EADRB2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250101014-A1 | BENZOISOTHIAZOLE AND BENZOISOXAZOLE COMPOUNDS FOR THE TREATMENT OF MENTAL DISORDERS | SUVEN LIFE SCIENCES LIMITED (IN) | 2025-03-27 | — | — | US | disclosed |
| US-20240009186-A1 | SOLUTION FOR ORAL ADMINISTRATION | OTSUKA PHARMACEUTICAL CO., LTD. | 2024-01-11 | — | — | US | disclosed |
| US-20220378943-A1 | ENHANCER POLYNUCLEOTIDE RESPONDING TO HEART FAILURE AND EXPRESSION VECTOR INCLUDING SAID ENHANCER POLYNUCLEOTIDE | OSAKA UNIVERSITY (JP) | 2022-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250101014-A1 | BENZOISOTHIAZOLE AND BENZOISOXAZOLE COMPOUNDS FOR THE TREATMENT OF MENTAL DISORDERS | GABRA5, GABBR1, GABRA2 | MAPT 242/4885TDP1 2133/4885KDM4E 2301/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.