Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 17/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | GHSR | Q92847 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2637596 | 0.78 | AR (0.53) | ARPGRRXRARXRBRXRG | |
| SCHEMBL30104699 | 0.76 | AR (0.48) | ARPGRRXRARXRBRXRG | |
| SCHEMBL16952198 | 0.75 | AR (0.56) | ARPGR | |
| SCHEMBL16961614 | 0.73 | AR (0.54) | ARPGRRXRARXRBRXRG | |
| SCHEMBL17843509 | 0.73 | RXRA (0.55) | ARPGRRXRARXRBRXRG | |
| SCHEMBL23877161 | 0.72 | AR (0.53) | ARPGRRXRARXRBRXRG | |
| SCHEMBL2473339 | 0.72 | NOTUM (0.57) | ARPGRRXRARXRBRXRG | |
| SCHEMBL221383 | 0.71 | AR (0.62) | ARPGR | |
| SCHEMBL30104645 | 0.71 | AR (0.55) | ARCYP2C19ABCB11ALBPGR | |
| SCHEMBL26364970 | 0.71 | AR (0.55) | ARCYP2C19ABCB11ALBPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4110322-A1 | SELECTIVE ANDROGEN RECEPTOR COVALENT ANTAGONISTS (SARCAS) AND METHODS OF USE THEREOF | University of Tennessee Research Foundation (US) | 2023-01-04 | — | — | EP | disclosed |