Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.37 |
| ▸ | MYC | P01106 | 1/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21326570 | 1.00 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2MAPK1KEAP1NFE2L2 | |
| SCHEMBL26040461 | 0.81 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2MAPK1KEAP1NFE2L2 | |
| SCHEMBL18703719 | 0.81 | KEAP1 (0.53) | ALDH1A1SMN1; SMN2MAPK1KEAP1NFE2L2 | |
| SCHEMBL30085262 | 0.81 | KEAP1 (0.53) | ALDH1A1SMN1; SMN2MAPK1KEAP1NFE2L2 | |
| SCHEMBL1945483 | 0.81 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2MAPK1KEAP1NFE2L2 | |
| SCHEMBL5256305 | 0.81 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2MAPK1KEAP1NFE2L2 | |
| SCHEMBL21349339 | 0.81 | KDM4E (0.47) | ALDH1A1SMN1; SMN2MAPK1POLBKDM4E | |
| SCHEMBL28906546 | 0.79 | KEAP1 (0.47) | ALDH1A1SMN1; SMN2MAPK1KEAP1NFE2L2 | |
| SCHEMBL31320230 | 0.78 | MEN1 (0.41) | ALDH1A1SMN1; SMN2MAPK1KEAP1NFE2L2 | |
| SCHEMBL21326520 | 0.77 | KEAP1 (0.46) | ALDH1A1KEAP1NFE2L2POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119504705-A | Non-peptide somatostatin 5 receptor agonists and uses thereof | 克林提克斯医药股份有限公司 | 2025-02-25 | — | — | CN | disclosed |
| CN-114585614-B | Non-peptide somatostatin 5 receptor agonists and uses thereof | 克林提克斯医药股份有限公司 | 2024-12-03 | — | — | CN | disclosed |
| WO-2024240108-A1 | ARYL UREA PARP1 INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | 上海海和药物研究开发股份有限公司 | 2024-11-28 | — | — | WO | disclosed |
| CN-109923116-B | [1,2,4] triazolo [1,5-a ] pyrimidine derivatives as PDE2 inhibitors | 詹森药业有限公司 | 2022-12-06 | — | — | CN | disclosed |